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Anti-PHYH Antibody (3G140)
还可以产品编号 TMAY-02575
Anti-PHYH Antibody (3G140) 是一种 Mouse 抗体，靶向 PHYH。Anti-PHYH Antibody (3G140) 可用于 IHC-P。
Anti-PHYH Antibody (3G140)
Anti-PHYH Antibody (3G140)
还可以产品编号 TMAY-02575
Anti-PHYH Antibody (3G140) 是一种 Mouse 抗体，靶向 PHYH。Anti-PHYH Antibody (3G140) 可用于 IHC-P。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-PHYH Antibody (3G140) is a Mouse antibody targeting PHYH. Anti-PHYH Antibody (3G140) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3G140 |
| 交叉反应 | Human |
| 验证活性 | Immunochemical staining of human PHYH in human kidney with mouse monoclonal antibody (1:30, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PHYH (rh PHYH; TMPY-03109; O14832; Ser31-Leu338). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. It converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Defects in PHYH can cause Refsum disease (RD). RD is an autosomal recessive disorder characterized clinically by a tetrad of abnormalities: retinitis pigmentosa, peripheral neuropathy, cerebellar ataxia, and elevated protein levels in the cerebrospinal fluid (CSF). Patients exhibit accumulation of the branched-chain fatty acid, phytanic acid, in blood and tissues. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human PHYH Protein (TMPY-03109) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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