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Anti-IRAK3 Antibody (3K815)
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产品编号 TMAC-02213
别名 IRAK-3, Irak3, Interleukin-1 receptor-associated kinase 3, Inactive IL-1 receptor-associated kinase 3, IL-1 receptor-associated kinase M (IRAK-M)
Anti-IRAK3 Antibody (3K815) 是一种 Rabbit 抗体，靶向 IRAK3。Anti-IRAK3 Antibody (3K815) 可用于 WB,IP。
Anti-IRAK3 Antibody (3K815)
Anti-IRAK3 Antibody (3K815)
还可以产品编号 TMAC-02213 别名 IRAK-3, Irak3, Interleukin-1 receptor-associated kinase 3, Inactive IL-1 receptor-associated kinase 3, IL-1 receptor-associated kinase M (IRAK-M)
Anti-IRAK3 Antibody (3K815) 是一种 Rabbit 抗体，靶向 IRAK3。Anti-IRAK3 Antibody (3K815) 可用于 WB,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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抗原信息
化学信息
| 产品描述 | Anti-IRAK3 Antibody (3K815) is a Rabbit antibody targeting IRAK3. Anti-IRAK3 Antibody (3K815) can be used in WB,IP. |
| 别名 | IRAK-3, Irak3, Interleukin-1 receptor-associated kinase 3, Inactive IL-1 receptor-associated kinase 3, IL-1 receptor-associated kinase M (IRAK-M) |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of IRAKM on different lysates using anti-IRAKM antibody at 1/1,000 dilution. Positive control: Lane 1: Human placenta, Lane 2: Human thyroid. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Interleukin-1 receptor (IL1R)-associated kinases (IRAKs) are important mediators in the signal transduction of Toll-like receptor (TLR) and IL1R family members, collectively referred to as TIRs. Binding of IL-1 to its cognate receptor results in the activation of the NFkB signaling pathway. An IL-1-dependent kinase termed IRAK-1 (for IL-1 receptor- associated kinase 1) coimmunoprecipitates with activated IL-1RI and is implicated as an upstream mediator of NFkB activation. A related Drosophila protein, Pelle, is a known upstream activator of Dorsal, the Drosophila homolog of NFkB. IRAK-2 is a proximal mediator of IL1, a component of the IL1R signaling complex, and is required for IL1R-induced NFkB activation. IRAK-4, like IRAK-1 and Pelle, has auto- and cross-phosphorylation kinase activity. IRAK-4 is strongly expressed in kidney and is also found in lung, testis, small intestine, breast, liver, and placenta. In contrast to the other IRAKs that are expressed in most cell types, IRAK-M is restricted to monocytic cells. IRAK-M mRNA transcripts are found predominantly in PBL and the monocytic cell lines U937 and THP-1. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 61 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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