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别名 pERp1, PACAP, MEDA-7, marginal zone B and B1 cell-specific protein, HSPC190
Anti-MZB1/PERP1 Antibody (1A338) 是一种 Rabbit 抗体,靶向 MZB1/PERP1。Anti-MZB1/PERP1 Antibody (1A338) 可用于 IHC-P。
Anti-MZB1/PERP1 Antibody (1A338) 是一种 Rabbit 抗体,靶向 MZB1/PERP1。Anti-MZB1/PERP1 Antibody (1A338) 可用于 IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
| 产品描述 | Anti-MZB1/PERP1 Antibody (1A338) is a Rabbit antibody targeting MZB1/PERP1. Anti-MZB1/PERP1 Antibody (1A338) can be used in IHC-P. |
| 别名 | pERp1, PACAP, MEDA-7, marginal zone B and B1 cell-specific protein, HSPC190 |
| Ig Type | Rabbit IgG |
| 克隆号 | 1A338 |
| 交叉反应 | Human |
| 特异性 | Human MZB1/PERP1 |
| 验证活性 | 1. Immunochemical staining of human MGC29506 in human spleen with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human MGC29506 in human small intestine with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:250-1:1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human PERP1 / MZB1 (rh PERP1 / MZB1; TMPY-03630; Q8WU39-1; Met 1- Thr 185). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. MZB1 is important for B cell function as a key regulator of antibody secretion, calcium homeostasis, and adhesion. MZB1 may play a central role in B cell neoplasms and is a potential target for future therapeutic interventions. Low MZB1 expression was an independent prognostic factor for recurrence after curative gastrectomy and was associated significantly with increased hematogenous recurrence. MZB1 acts as a suppressor of gastric cancer (GC). Low MZB1 expression in the primary GC tissue is predictive of recurrence after curative resection. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human PERP1 / MZB1 Protein (TMPY-03630) |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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