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Anti-Patched Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Patched。Anti-Patched Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。
Anti-Patched Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Patched。Anti-Patched Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,175 | 5日内发货 | |
100 μL | ¥ 1,965 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
产品描述 | Anti-Patched Polyclonal Antibody is a Rabbit antibody targeting Patched. Anti-Patched Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA. |
Ig Type | IgG |
交叉反应 | Human,Mouse (predicted:Rat,Chicken,Cow,Horse,Rabbit) |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Membrane. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | PTCH (Patched protein homolog 1) is a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). PTCH associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal.PTCH has a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis. PTCH is expressed in the adult brain, lung, liver, heart, placenta, skeletal muscle, pancreas and kidney. It is also expressed in tumor cells but not in normal skin. During development PTCH is found in all major target tissues of sonic hedgehog, such as the ventral neural tube, somites, and tissues surrounding the zone of polarizing activity of the limb bud. Defects in PTCH are probably the cause of basal cell nevus syndrome also known as Gorlin syndrome or Gorlin-Goltz syndrome. |
免疫原 | KLH conjugated synthetic peptide: human Patched/PTCH |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | PTC & Wnt pathway,Cell Cycle Inhibitors,Neurogenesis,Surface Molecules |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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