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Anti-Patched Polyclonal Antibody

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Anti-Patched Polyclonal Antibody
产品编号 TMAB-01337

Anti-Patched Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Patched。Anti-Patched Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

Anti-Patched Polyclonal Antibody

Anti-Patched Polyclonal Antibody

Rating icon 还可以
Anti-Patched Polyclonal Antibody
产品编号 TMAB-01337

Anti-Patched Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Patched。Anti-Patched Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Patched Polyclonal Antibody is a Rabbit antibody targeting Patched. Anti-Patched Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Ig Type
IgG
交叉反应
Human,Mouse (predicted:Rat,Chicken,Cow,Horse,Rabbit)
应用
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景PTCH (Patched protein homolog 1) is a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). PTCH associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal.PTCH has a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis. PTCH is expressed in the adult brain, lung, liver, heart, placenta, skeletal muscle, pancreas and kidney. It is also expressed in tumor cells but not in normal skin. During development PTCH is found in all major target tissues of sonic hedgehog, such as the ventral neural tube, somites, and tissues surrounding the zone of polarizing activity of the limb bud. Defects in PTCH are probably the cause of basal cell nevus syndrome also known as Gorlin syndrome or Gorlin-Goltz syndrome.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Patched/PTCH
抗原种属
Human
基因ID
Uniprot ID
研究领域
PTC & Wnt pathway,Cell Cycle Inhibitors,Neurogenesis,Surface Molecules
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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