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Anti-Adiponectin Antibody (6Q759)

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货号 TMAB-02342

Anti-Adiponectin Antibody (6Q759) 是一种 Mouse 抗体,靶向 Adiponectin。Anti-Adiponectin Antibody (6Q759) 可用于 IHC-P,IHC-Fr,IF。

Anti-Adiponectin Antibody (6Q759)

Anti-Adiponectin Antibody (6Q759)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02342

Anti-Adiponectin Antibody (6Q759) 是一种 Mouse 抗体,靶向 Adiponectin。Anti-Adiponectin Antibody (6Q759) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
200 μg
¥ 5,585
5日内发货
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-Adiponectin Antibody (6Q759) is a Mouse antibody targeting Adiponectin. Anti-Adiponectin Antibody (6Q759) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
6Q759
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Secreted.
组织特异性Synthesized exclusively by adipocytes and secreted into plasma.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Adiponectin: A protein hormone produced and secreted exclusively by adipocytes (fat cells) that regulates the metabolism of lipids and glucose. Adiponectin influences the body's response to insulin. Adiponectin also has antiinflammatory effects on the cells lining the walls of blood vessels. High blood levels of adiponectin are associated with a reduced risk of heart attack. Low levels of adiponectin are found in people who are obese (and who are at increased risk of a heart attack). Adipocytes produce and secrete a number of proteins, including leptin, adipsin, properdin, and tumor necrosis factor (TNF). An adipose tissue-specific factor was isolated and termed APM1 (AdiPose Most abundant gene transcript 1). The protein product of APM1 is adiponectin. The APM1 gene maps to chromosome 3q27.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Adiponectin
抗原种属
Human
基因名称
ADIPOQ
基因ID
蛋白名称
Adiponectin
Uniprot ID
功能
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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