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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GLIS2 Polyclonal Antibody

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货号 TMAB-06508

Anti-GLIS2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GLIS2。Anti-GLIS2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-GLIS2 Polyclonal Antibody

Anti-GLIS2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06508

Anti-GLIS2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GLIS2。Anti-GLIS2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-GLIS2 Polyclonal Antibody is a Rabbit antibody targeting GLIS2. Anti-GLIS2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus speckle. Cytoplasm.
组织特异性Expressed at high levels in kidney and at low levels in heart, lung and placenta. Expressed in colon.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景GLIS2 is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family. By recruiting the corepressors CtBP1 and HDAC3, GLIS2 represses the transcriptional activation mediated by ∫-catenin in the Wnt pathway. GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation. Mutations of GLIS2 may be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis. GLIS2 contains five tandem Cys(2)-His(2) zinc finger motifs that exhibit the highest homology to those of members of the GLI and Zic subfamilies of Krüppel-like proteins. GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GLIS2
抗原种属
Human
基因名称
GLIS2
基因ID
84662
蛋白名称
Zinc finger protein GLIS2
Uniprot ID
Q9BZE0
功能
Can act either as a transcription repressor or as a transcription activator, depending on the cell context. Represses the transcriptional activation mediated by CTNNB1 in the Wnt pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation.
化学信息
分子量Theoretical: 56 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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