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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CRK Polyclonal Antibody

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货号 TMAB-04678

Anti-CRK Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CRK。Anti-CRK Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CRK Polyclonal Antibody

Anti-CRK Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04678

Anti-CRK Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CRK。Anti-CRK Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-CRK Polyclonal Antibody is a Rabbit antibody targeting CRK. Anti-CRK Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cell membrane. Note=Translocated to the plasma membrane upon cell adhesion.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Crk
抗原种属
Human
基因名称
CRK
基因ID
1398
蛋白名称
Adapter molecule crk
Uniprot ID
P46108
功能
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
化学信息
分子量Theoretical: 33 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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