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Anti-CD44 Polyclonal Antibody

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货号 TMAB-00369

别名 Pgp1, MIC4, MDU3, MDU2, MC56, LHR, IN, HUTCH-I, HCELL, ECMR-III, CSPG8, CDW44, CD44 molecule (Indian blood group)

Anti-CD44 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CD44。Anti-CD44 Polyclonal Antibody 可用于 WB。

Anti-CD44 Polyclonal Antibody

Anti-CD44 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-00369 别名 Pgp1, MIC4, MDU3, MDU2, MC56, LHR, IN, HUTCH-I, HCELL, ECMR-III, CSPG8, CDW44, CD44 molecule (Indian blood group)

Anti-CD44 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CD44。Anti-CD44 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-CD44 Polyclonal Antibody is a Rabbit antibody targeting CD44. Anti-CD44 Polyclonal Antibody can be used in WB.
别名Pgp1, MIC4, MDU3, MDU2, MC56, LHR, IN, HUTCH-I, HCELL, ECMR-III, CSPG8, CDW44, CD44 molecule (Indian blood group)
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
验证活性
Sample:
Lane 1: Hela (Human) Cell Lysate at 30 μg
Lane 2: Panc-1 (Human) Cell Lysate at 30 μg
Lane 3: Huvec (Human) Cell Lysate at 30 μg
Lane 4: A549 (Human) Cell Lysate at 30 μg
Primary: Anti-CD44 (TMAB-00369) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 83 kDa
Observed band size: 83 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges.
组织特异性Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD44
抗原种属
Human
基因名称
CD44
基因ID
蛋白名称
CD44 antigen
Uniprot ID
研究领域
Tumor biomarkers,CD markers,Adhesion,CD markers ELISA kits,T Lymphocytic Lineage,Dendritic Cell Lineage,Neutrophil Lineage,Surface Molecules
功能
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
化学信息
分子量Theoretical: 85 kDa. Actual: 80-95 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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