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Anti-APAF1 Monoclonal Antibody (8D809) 是一种 Mouse 抗体,靶向 APAF1。Anti-APAF1 Monoclonal Antibody (8D809) 可用于 IF,FCM。
别名 CED4, APAF-1
Anti-APAF1 Monoclonal Antibody (8D809) 是一种 Mouse 抗体,靶向 APAF1。Anti-APAF1 Monoclonal Antibody (8D809) 可用于 IF,FCM。

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| 产品描述 | Anti-APAF1 Monoclonal Antibody (8D809) is a Mouse antibody targeting APAF1. Anti-APAF1 Monoclonal Antibody (8D809) can be used in IF,FCM. |
| 别名 | CED4, APAF-1 |
| Ig Type | IgG2b |
| 克隆号 | 8D809 |
| 反应种属 | Human |
| 应用 | IFFCM |
| 推荐剂量 | IF: 1/100-1/500; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human APAF1 (AA: 1138-1237) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | APAF1 |
| 基因ID | |
| 蛋白名称 | Apoptotic protease-activating factor 1 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |