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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-NFATC4 (Ser168+Ser170) Polyclonal Antibody

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货号 TMAB-11041

Anti-Phospho-NFATC4 (Ser168+Ser170) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-NFATC4 (Ser168+Ser170)。Anti-Phospho-NFATC4 (Ser168+Ser170) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-NFATC4 (Ser168+Ser170) Polyclonal Antibody

Anti-Phospho-NFATC4 (Ser168+Ser170) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11041

Anti-Phospho-NFATC4 (Ser168+Ser170) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-NFATC4 (Ser168+Ser170)。Anti-Phospho-NFATC4 (Ser168+Ser170) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Phospho-NFATC4 (Ser168+Ser170) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NFATC4 (Ser168+Ser170). Anti-Phospho-NFATC4 (Ser168+Ser170) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
组织特异性Highly expressed in placenta, lung, kidney, testis and ovary. Weakly expressed in spleen and thymus. Not expressed in peripheral blood lymphocytes. Detected in hippocampus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The product of this gene is a member of the nuclearfactors of activated T cells DNA-binding transcription complex.This complex consists of at least two components: a preexistingcytosolic component that translocates to the nucleus upon T cellreceptor (TCR) stimulation and an inducible nuclear component.Other members of this family of nuclear factors of activated Tcells also participate in the formation of this complex. Theproduct of this gene plays a role in the inducible expression ofcytokine genes in T cells, especially in the induction of the IL-2and IL-4. Alternatively spliced transcript variants encodingdifferent isoforms have been noted for this gene. [provided byRefSeq, Oct 2008].
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human NFATC4 around the phosphorylation site of Ser168 + Ser170
抗原种属
Human
基因名称
NFATC4
基因ID
4776
蛋白名称
Nuclear factor of activated T-cells, cytoplasmic 4
Uniprot ID
Q14934
功能
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.
化学信息
分子量Theoretical: 95 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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