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FGF-21 Protein, Hamster, Recombinant (His)

产品编号 TMPY-05794

FGF-21 Protein, Hamster, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.16 kDa and the accession number is A0A1U7RD97.

FGF-21 Protein, Hamster, Recombinant (His)

FGF-21 Protein, Hamster, Recombinant (His)

产品编号 TMPY-05794
FGF-21 Protein, Hamster, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.16 kDa and the accession number is A0A1U7RD97.
规格价格库存数量
100 μg
¥ 3,430
5日内发货
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常见问题解答
如果低于说明书给出的最高溶解度情况下,产品仍未溶解怎么办?
建议您使用一些辅助溶解方法,如水浴加热至 45℃ 或用超声震荡,加速粉末溶解。
购买多次产品,发现颜色不同,怎么办?
首先请您确认批次,如果是同一个批次产品,请联系技术同事核查产品颜色。如果是不同批次,请您放心,颜色不同可能是生产工艺不同而造成的,生产过程中的操作、温度、时间等因素可能会影响产品的颜色。如果您对该批次有疑虑,可在官网下载相应的质检报告,我们是对产品质量负责的。
抑制剂产品应如何储存?
粉末储存在 -20℃,可以存 3 年以上。 母液一般储存于 -80℃,可以存 1 年以上,建议多分装几管,避免反复冻融。 常用的存于 4℃,可放一周以上。
溶解度中写的“< 1 mg/mL refers to the slightly soluble or insoluble ”是什么意思?
这句话指的是,如果溶解度 < 1 mg/mL,那我们就认为它是微溶或不溶的,这是针对写的“DMSO:Insoluble”或“DMSO:slightly soluble”这类化合物的。
超声久了会不会对化合物的结构有影响?
建议以较低频率对化合物进行超声,不会对化合物的结构造成影响。
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产品信息

生物活性
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述
FGF-21 Protein, Hamster, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.16 kDa and the accession number is A0A1U7RD97.
种属
Hamster
表达系统
HEK293 Cells
标签C-His
蛋白编号A0A1U7RD97
别名
成纤维细胞生长因子,fibroblast growth factor 21
蛋白构建
A DNA sequence encoding the hamster FGF21 (XP_005084765.1) (Met1-Ser209) was expressed with a polyhistide tag at the C-terminus. Predicted N terminal: Arg29
蛋白纯度
> 95 % as determined by SDS-PAGE.
分子量21.16 kDa (predicted)
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice.
研究背景
Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.

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