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Anti-SCLT1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 SCLT1。Anti-SCLT1 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-SCLT1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 SCLT1。Anti-SCLT1 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-SCLT1 Polyclonal Antibody 2 is a Rabbit antibody targeting SCLT1. Anti-SCLT1 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Cell periphery. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | SCLT1 (sodium channel and clathrin linker 1), also known as CAP1A or hCAP-1A, is a 688 amino acid cytoplasmic protein that acts as a linker between the voltage-gated sodium channel, Na+ CP type X? and clathrin. SCLT1 is abundantly expressed in DRG (dorsal root ganglia) neurons and colocalizes with Na+ CP type X? SCLT1 regulates Na+ CP type X?channel activity by promoting channel internalization. SCLT1 exists as four alternatively spliced isoforms and is encoded by a gene located on human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. |
| 免疫原 | KLH conjugated synthetic peptide: human SCLT1 |
| 抗原种属 | Human |
| 基因名称 | SCLT1 |
| 基因ID | |
| 蛋白名称 | Sodium channel and clathrin linker 1 |
| Uniprot ID | |
| 功能 | Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization. |
| 分子量 | Theoretical: 81 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |