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Anti-Phospho-PKCα (Thr638) Antibody (4G731)
还可以产品编号 TMAY-01662
Anti-Phospho-PKCα (Thr638) Antibody (4G731) 是一种 Rabbit 抗体，靶向 Phospho-PKCα (Thr638)。Anti-Phospho-PKCα (Thr638) Antibody (4G731) 可用于 WB。
Anti-Phospho-PKCα (Thr638) Antibody (4G731)
Anti-Phospho-PKCα (Thr638) Antibody (4G731)
还可以产品编号 TMAY-01662
Anti-Phospho-PKCα (Thr638) Antibody (4G731) 是一种 Rabbit 抗体，靶向 Phospho-PKCα (Thr638)。Anti-Phospho-PKCα (Thr638) Antibody (4G731) 可用于 WB。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-PKCα (Thr638) Antibody (4G731) is a Rabbit antibody targeting Phospho-PKCα (Thr638). Anti-Phospho-PKCα (Thr638) Antibody (4G731) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4G731 |
| 交叉反应 | Human; Predicted to React with:>Human Phospho-PKCα (Thr638); Predicted to React with: Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Bovine |
| 验证活性 | 1. Western blot analysis of extracts from HEK-293, untreated (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-PKCα (Thr638) Antibody, Rabbit MAb at 1:1000 dilution. 2. Western blot analysis of extracts from HEK-293, using Phospho-PKCα (Thr638) Antibody, Rabbit MAb and other brands’ antibodies (Company C) at dilution of 1:1000 and 1:20000. |
| 应用 | WB |
| 推荐剂量 | WB: 1:1000-1:5000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Thr638 of human Phospho-PKCα. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| 研究背景 | Protein kinase C alpha (PRKCA) is involved in multiple functions and has been implicated in heart failure risks and treatment outcomes. The protein kinase C alpha (PRKCA) gene, coding for a Th17-cell-selective kinase, shows a complex splicing pattern, with at least 2 stable alternative transcripts characterized by an alternative upstream polyadenylation site. Polymorphisms in this gene were associated with several conditions, including multiple sclerosis, asthma, schizophrenia, and cancer. The protein kinase C alpha (PRKCA) gene, encoding a Th17-cell-selective kinase, was repeatedly associated with multiple sclerosis (MS).PRKCA polymorphisms and gene-gene interactions within the ACEi pathway affect the antihypertensive responses to enalapril. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic phosphopeptide corresponding to residues around Thr638 of human Phospho-PKCα. |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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