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Anti-ULBP-2 Antibody (4Z93) 是一种 Rabbit 抗体,靶向 ULBP-2。Anti-ULBP-2 Antibody (4Z93) 可用于 IHC-P。
Anti-ULBP-2 Antibody (4Z93) 是一种 Rabbit 抗体,靶向 ULBP-2。Anti-ULBP-2 Antibody (4Z93) 可用于 IHC-P。
产品描述 | Anti-ULBP-2 Antibody (4Z93) is a Rabbit antibody targeting ULBP-2. Anti-ULBP-2 Antibody (4Z93) can be used in IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 4Z93 |
交叉反应 | Human |
验证活性 | 1. Immunochemical staining of human ULBP2 in human renal carcinoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human ULBP2 in human hepatoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human ULBP2 in human gastric cancer with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
应用 | IHC-P |
推荐剂量 | IHC-P: 1:100-1:500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ULBP2 / N2DL-2 (rh ULBP2 / N2DL-2; TMPY-02333; Q9BZM5; Met1-Ser217). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. |
偶联 | Unconjugated |
免疫原 | Recombinant Human ULBP2 / N2DL-2 protein (TMPY-02333) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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