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Anti-Fibronectin Antibody (5U855)
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产品编号 TMAH-00447
别名 FN1, Fibronectin
Anti-Fibronectin Antibody (5U855) 是一种抗体，靶向 Fibronectin。Anti-Fibronectin Antibody (5U855) 可用于 ELISA, FCM。
Anti-Fibronectin Antibody (5U855)
Anti-Fibronectin Antibody (5U855)
还可以产品编号 TMAH-00447 别名 FN1, Fibronectin
Anti-Fibronectin Antibody (5U855) 是一种抗体，靶向 Fibronectin。Anti-Fibronectin Antibody (5U855) 可用于 ELISA, FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Fibronectin Antibody (5U855) is an antibody targeting Fibronectin. Anti-Fibronectin Antibody (5U855) can be used in ELISA, FCM. |
| 别名 | FN1, Fibronectin |
| Ig Type | Mouse IgG2a |
| 克隆号 | 5U855 |
| 交叉反应 | Human |
| 验证活性 | Overlay Peak curve showing 3T3 cells stained with TMAH-00447 (red line) at 1:50.The cells were fixed in 4% formaldehyde (15min) and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed. |
| 应用 | |
| 推荐剂量 | FCM:1:20-1:500. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human FN1 Protein |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Cancer, Cardiovascular, Developmental biology, Signal transduction, Stem cells |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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