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Anti-SFPQ Antibody (1W928) 是一种 Rabbit 抗体,靶向 SFPQ。Anti-SFPQ Antibody (1W928) 可用于 WB,IHC,ICC,IF。
Anti-SFPQ Antibody (1W928) 是一种 Rabbit 抗体,靶向 SFPQ。Anti-SFPQ Antibody (1W928) 可用于 WB,IHC,ICC,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-SFPQ Antibody (1W928) is a Rabbit antibody targeting SFPQ. Anti-SFPQ Antibody (1W928) can be used in WB,IHC,ICC,IF. |
别名 | Splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated), Splicing factor proline/glutamine rich, Splicing factor proline and glutamine rich, Splicing factor, SFPQ_HUMAN, Sfpq, PTB-associated-splicing factor, PTB associated splicing factor, PSF, Protein phosphatase 1 regulatory subunit 140, proline- and glutamine-rich, PPP1R140, POMP100, Polypyrimidine tract-binding protein-associated-splicing factor, Polypyrimidine tract binding protein associated splicing factor, hPOMp100, DNA-binding p52/p100 complex, DNA binding p52/p100 complex 100 kDa subunit, 100 kDa subunit, 100 kDa DNA-pairing protein, 100 kDa DNA pairing protein |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of SFPQ on different lysates using anti-SFPQ antibody at 1/1,000 dilution. Positive control: Lane 1: K562, Lane 2: Daudi, Lane 3: Mouse testis, Lane 4: Mouse lung. 2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-SFPQ antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-SFPQ antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-SFPQ antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-SFPQ antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-SFPQ antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:10-50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Involved in regulation of signal-induced alternative splicing. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. May be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs. SFPQ may be involved in homologous DNA pairing; in vitro, promotes the invasion of ssDNA between a duplex DNA and produces a D-loop formation. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 100 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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