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R-Spondin 3/RSPO3 Protein, Human, Recombinant (hFc & His)

R-Spondin 3/RSPO3 Protein, Human, Recombinant (hFc & His)

产品编号 TMPJ-00163
别名: Protein with TSP type-1 repeat, RSPO3, R-spondin-3, Roof plate-specific spondin-3, CRISTIN1, THSD2, Thrombospondin type-1 domain-containing protein 2, PWTSR

R-spondin-3 (RSPO3), also known as Protein with TSP type-1 repeat, Roof plate-specific spondin-3, Thrombospondin type-1 domain-containing protein 2, PWTSR, THSD2 and CRISTIN1, is a member of the thrombospondin type 1 repeat supergene family. RSPO3 is a secreted protein and widely expressed in many tissues. RSPO3 contains two Furin-like repeats which have been found in a variety of eukaryotic proteins involved in the mechanism of signal transduction by receptor tyrosine kinases, and one TSP type-1 domain, RSPO3 founctions as a activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Otherwise, RSPO3 may negatively regulate the TGF-beta pathway.

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R-Spondin 3/RSPO3 Protein, Human, Recombinant (hFc & His)
规格 价格/CNY 货期 数量
10 μg ¥ 820 5日内发货
50 μg ¥ 2,480 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
夏季3重特惠
药物设计专题培训
Chloroquine限时半价
产品目录号及名称: R-Spondin 3/RSPO3 Protein, Human, Recombinant (hFc & His) (TMPJ-00163)
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产品描述 R-spondin-3 (RSPO3), also known as Protein with TSP type-1 repeat, Roof plate-specific spondin-3, Thrombospondin type-1 domain-containing protein 2, PWTSR, THSD2 and CRISTIN1, is a member of the thrombospondin type 1 repeat supergene family. RSPO3 is a secreted protein and widely expressed in many tissues. RSPO3 contains two Furin-like repeats which have been found in a variety of eukaryotic proteins involved in the mechanism of signal transduction by receptor tyrosine kinases, and one TSP type-1 domain, RSPO3 founctions as a activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Otherwise, RSPO3 may negatively regulate the TGF-beta pathway.
种属 Human
表达系统 HEK293 Cells
标签 C-hFc-6xHis
蛋白编号 Q9BXY4
别名 Protein with TSP type-1 repeat, RSPO3, R-spondin-3, Roof plate-specific spondin-3, CRISTIN1, THSD2, Thrombospondin type-1 domain-containing protein 2, PWTSR
氨基酸序列 Gln22-Val201
蛋白构建 Gln22-Val201
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
分子量 61 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 R-spondin-3 (RSPO3), also known as Protein with TSP type-1 repeat, Roof plate-specific spondin-3, Thrombospondin type-1 domain-containing protein 2, PWTSR, THSD2 and CRISTIN1, is a member of the thrombospondin type 1 repeat supergene family. RSPO3 is a secreted protein and widely expressed in many tissues. RSPO3 contains two Furin-like repeats which have been found in a variety of eukaryotic proteins involved in the mechanism of signal transduction by receptor tyrosine kinases, and one TSP type-1 domain, RSPO3 founctions as a activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Otherwise, RSPO3 may negatively regulate the TGF-beta pathway.

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Keywords

R-Spondin 3/RSPO3 Protein, Human, Recombinant (hFc & His) Protein with TSP type-1 repeat RSPO3 R-spondin-3 THSD 2 Roof plate-specific spondin-3 CRISTIN-1 CRISTIN 1 CRISTIN1 THSD2 Thrombospondin type-1 domain-containing protein 2 RSPO-3 RSPO 3 THSD-2 PWTSR recombinant recombinant-proteins proteins protein

 

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