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IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)
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货号 TMPK-00512
别名 IL1RRP, IL-18Ra, IL18Ra, IL18R1, IL-18 R1, IL-18 R α, IL-18 R alpha, IL-1 Rrp, IL-1 R5, CD218a
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 36.45 kDa and the accession number is A0A2K5V3J9.
其他形式的 “IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)”:
IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPK-00512 别名 IL1RRP, IL-18Ra, IL18Ra, IL18R1, IL-18 R1, IL-18 R α, IL-18 R alpha, IL-1 Rrp, IL-1 R5, CD218a
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 36.45 kDa and the accession number is A0A2K5V3J9.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 358 | 6-8日内发货 | |
| 10 μg | ¥ 573 | 6-8日内发货 | |
| 20 μg | ¥ 938 | 5日内发货 | |
| 50 μg | ¥ 1,830 | 5日内发货 | |
| 100 μg | ¥ 3,100 | 5日内发货 | |
| 200 μg | ¥ 5,620 | 5日内发货 | |
| 500 μg | ¥ 12,400 | 5日内发货 |
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| 产品描述 | Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 36.45 kDa and the accession number is A0A2K5V3J9. |
| 生物活性 | Cynomolgus IL-18 R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human IL-18, No Tag with an affinity constant of 2.02 nM as determined in SPR assay. |
| 研究背景 | Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. |
| 种属 | Cynomolgus |
| 表达系统 | HEK293 Cells |
| 标签 | C-His |
| 蛋白编号 | A0A2K5V3J9 |
| 蛋白构建 | Cys22-Gly329 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | IL1RRP, IL-18Ra, IL18Ra, IL18R1, IL-18 R1, IL-18 R α, IL-18 R alpha, IL-1 Rrp, IL-1 R5, CD218a |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 36.45 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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