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SDF-1 alpha/CXCL12 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P48061.

| 规格 | 价格 | 库存 | 数量 | 
|---|
| 生物活性 | Loaded Recombinant Human CXCR4 (N-Fc) on Pro-A Biosensor, can bind Recombinant Human CXCL12 with an affinity constant of 8.4 uM as determined in BLI assay. (Regularly tested) | 
| 产品描述 | SDF-1 alpha/CXCL12 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P48061. | 
| 种属 | Human | 
| 表达系统 | E. coli | 
| 蛋白编号 | P48061 | 
| 别名 | TPAR1,TLSF,SDF-1α,SDF-1,SDF1,SCYB12,PBSF,IRH,chemokine (C-X-C motif) ligand 12 | 
| 蛋白构建 | Lys22-Lys89 | 
| 蛋白纯度 | > 95% as determined by SDS-PAGE | 
| 分子量 | 8 kDa (Predicted); 10 kDa (Reducing conditions) | 
| 内毒素 | < 0.01 EU/μg of the protein as determined by the LAL method. | 
| 蛋白性状 | Lyophilized powder | 
| 缓冲液 | Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4. | 
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. | 
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| 研究背景 | Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1α and SDF1β are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface, and can also bind syndecan4. SDF1 is known to influence lymphopoiesis, regulate patterning and cell number of neural progenitors, and promote angiogenesis. It also enhances the survival of myeloid progenitor cells. |