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Butylated hydroxytoluene

Name: Butylated hydroxytoluene
Brand: TargetMol
SKU: T0935
Price: 158 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 99.72%

货号 T0935Cas号 128-37-0

别名 BHT FCC/NF, 2,6-二叔丁基对甲酚

Butylated hydroxytoluene (BHT FCC/NF) 是一种抗氧化剂，广泛用于食品、化妆品和工业液体中。它是一种铁死亡抑制剂。

Butylated hydroxytoluene

一键复制产品信息

很棒

纯度: 99.72%

货号 T0935 别名 BHT FCC/NF, 2,6-二叔丁基对甲酚Cas号 128-37-0

Butylated hydroxytoluene (BHT FCC/NF) 是一种抗氧化剂，广泛用于食品、化妆品和工业液体中。它是一种铁死亡抑制剂。

规格	价格	库存
50 mg	¥ 158	现货
100 mg	¥ 216	现货
500 mg	¥ 486	现货
1 g	¥ 706	现货
5 g	¥ 1,730	现货
1 mL x 10 mM (in DMSO)	¥ 306	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.72%

颜色: 白色

性状: Solid

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资源下载:

COA HNMR HPLC LCMS 产品操作手册

产品介绍

Butylated hydroxytoluene AI Summary

Butylated hydroxytoluene displays significant antioxidant activity across a multitude of assays and concentrations. It demonstrates a notable ability to inhibit lipid peroxidation in various tissues, including rat brain and liver microsomes, with IC50 values ranging from 0.1 µg/mL to 59,000 nM. Its time-dependent antioxidative properties are evident in AAPH-induced MDA assays and other experimental setups, showing decreased activity over longer incubations. Additionally, Butylated hydroxytoluene exhibits a range of radical scavenging activities, including DPPH, ABTS, nitric oxide, hydroxyl, and superoxide radicals. It shows variable efficacy in different assays, with IC50 values for DPPH radical scavenging reported between 16.47 µg/mL and 90900 nM. It also inhibits lipid peroxidation induced by ferrous ions and AAPH in different models. Moreover, Butylated hydroxytoluene has shown neuroprotective and cytoprotective effects, demonstrated by its ability to protect cerebellar granule cells from iodoacetate-induced toxicity and to inhibit cellular death in C6 glial cells. It has been reported to enhance recovery from coma, evidenced by improved survival times and behavioral responses in mice. The compound also exhibits anti-hypoxic, anti-inflammatory, and enzyme regulatory activities. It inhibits human erythrocyte CA1 and CA2 esterase activity, as well as platelet aggregation induced by platelet-activating factors. Furthermore, Butylated hydroxytoluene has a potential use in reducing oxidative stress and protecting against cellular damage in ischemic conditions. Finally, the compound shows antibacterial and antibiofilm activities, against strains like Vibrio harveyi, and demonstrates synergistic effects when combined with other agents. Its ability to inhibit quorum sensing, reduce biofilm formation, and enhance cell viability in infected organisms highlights its potential therapeutic applications in infectious diseases..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Butylated hydroxytoluene (BHT FCC/NF) is an antioxidant widely used in food, cosmetics and industrial liquids. It is a ferroptosis inhibitor.
别名	BHT FCC/NF, 2,6-二叔丁基对甲酚

化学信息

分子量	220.35
分子式	C₁₅H₂₄O
CAS No.	128-37-0
Smiles	OC=1C(=CC(=CC1C(C)(C)C)C)C(C)(C)C
密度	1.048 g/cm3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 242.5 mg/mL (1100.52 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5382 mL	22.6912 mL	45.3823 mL	226.9117 mL
5 mM	0.9076 mL	4.5382 mL	9.0765 mL	45.3823 mL
10 mM	0.4538 mL	2.2691 mL	4.5382 mL	22.6912 mL
20 mM	0.2269 mL	1.1346 mL	2.2691 mL	11.3456 mL
50 mM	0.0908 mL	0.4538 mL	0.9076 mL	4.5382 mL
100 mM	0.0454 mL	0.2269 mL	0.4538 mL	2.2691 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法： 取 100 μL DMSO 母液，添加 400 μL PEG300 混匀澄清，再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH₂O 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

Inhibitor inhibit Ferroptosis Butylated hydroxytoluene Antioxidant

Butylated hydroxytoluene

Butylated hydroxytoluene