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顶部相关产品产品介绍化学信息储存和溶解信息计算器

Butylated hydroxytoluene

Synonyms: BHT FCC/NF, 2,6-二叔丁基对甲酚
货号 T0935Cas号 128-37-0 一键复制产品信息纯度: 99.72%
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Butylated hydroxytoluene (BHT FCC/NF) 是一种抗氧化剂，广泛用于食品、化妆品和工业液体中。它是一种铁死亡抑制剂。

Butylated hydroxytoluene

一键复制产品信息
Rating icon 很棒

纯度: 99.72%

货号 T0935Cas号 128-37-0

别名 BHT FCC/NF, 2,6-二叔丁基对甲酚

Butylated hydroxytoluene (BHT FCC/NF) 是一种抗氧化剂，广泛用于食品、化妆品和工业液体中。它是一种铁死亡抑制剂。

Butylated hydroxytoluene
其他形式的 “Butylated hydroxytoluene”:
Butylated hydroxytoluene (Standard)
Butylated hydroxytoluene-D24
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规格价格库存数量
50 mg
¥ 158
现货
100 mg
¥ 216
现货
500 mg
¥ 486
现货
1 g
¥ 706
现货
5 g
¥ 1,730
现货
1 mL x 10 mM (in DMSO)
¥ 306
现货
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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

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常见问题解答
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纯度: 99.72%
颜色: 白色
性状: Solid
资源下载: COA HPLC LCMS HNMR产品操作手册

产品介绍

Butylated hydroxytoluene AI Summary
Butylated hydroxytoluene displays significant antioxidant activity across a multitude of assays and concentrations. It demonstrates a notable ability to inhibit lipid peroxidation in various tissues, including rat brain and liver microsomes, with IC50 values ranging from 0.1 µg/mL to 59,000 nM. Its time-dependent antioxidative properties are evident in AAPH-induced MDA assays and other experimental setups, showing decreased activity over longer incubations. Additionally, Butylated hydroxytoluene exhibits a range of radical scavenging activities, including DPPH, ABTS, nitric oxide, hydroxyl, and superoxide radicals. It shows variable efficacy in different assays, with IC50 values for DPPH radical scavenging reported between 16.47 µg/mL and 90900 nM. It also inhibits lipid peroxidation induced by ferrous ions and AAPH in different models. Moreover, Butylated hydroxytoluene has shown neuroprotective and cytoprotective effects, demonstrated by its ability to protect cerebellar granule cells from iodoacetate-induced toxicity and to inhibit cellular death in C6 glial cells. It has been reported to enhance recovery from coma, evidenced by improved survival times and behavioral responses in mice. The compound also exhibits anti-hypoxic, anti-inflammatory, and enzyme regulatory activities. It inhibits human erythrocyte CA1 and CA2 esterase activity, as well as platelet aggregation induced by platelet-activating factors. Furthermore, Butylated hydroxytoluene has a potential use in reducing oxidative stress and protecting against cellular damage in ischemic conditions. Finally, the compound shows antibacterial and antibiofilm activities, against strains like Vibrio harveyi, and demonstrates synergistic effects when combined with other agents. Its ability to inhibit quorum sensing, reduce biofilm formation, and enhance cell viability in infected organisms highlights its potential therapeutic applications in infectious diseases..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
Butylated hydroxytoluene (BHT FCC/NF) is an antioxidant widely used in food, cosmetics and industrial liquids. It is a ferroptosis inhibitor.
别名
BHT FCC/NF, 2,6-二叔丁基对甲酚
化学信息
分子量220.35
分子式C15H24O
CAS No.128-37-0
SmilesOC=1C(=CC(=CC1C(C)(C)C)C)C(C)(C)C
密度1.048 g/cm3
储存&溶解度
存储

Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息
DMSO: 242.5 mg/mL (1100.52 mM), Sonication is recommended.
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM4.5382 mL22.6912 mL45.3823 mL226.9117 mL
5 mM0.9076 mL4.5382 mL9.0765 mL45.3823 mL
10 mM0.4538 mL2.2691 mL4.5382 mL22.6912 mL
20 mM0.2269 mL1.1346 mL2.2691 mL11.3456 mL
50 mM0.0908 mL0.4538 mL0.9076 mL4.5382 mL
100 mM0.0454 mL0.2269 mL0.4538 mL2.2691 mL
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

InhibitorinhibitFerroptosisButylated hydroxytolueneAntioxidant
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