IL-36 gamma Protein, Mouse, Recombinant

Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.

规格	价格/CNY		数量
10 μg	￥ 1,570	5日内发货
50 μg	￥ 4,740	5日内发货
500 μg	￥ 15,800	5日内发货
1 mg	￥ 23,700	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 1,570

5日内发货

50 μg

￥ 4,740

5日内发货

500 μg

￥ 15,800

5日内发货

1 mg

￥ 23,700

5日内发货

产品描述

种属	Mouse
表达系统	E. coli
标签	Tag Free
蛋白编号	Q8R460
别名	白介素, Interleukin-36 γ, IL-1F9, Interleukin-36 gamma, IL-1 epsilon, IL36G, IL-1-related protein 2, IL-1 ε, IL-1RP2, Interleukin-1 homolog 1, 白细胞介素, IL-1H1, IL-36 γ
氨基酸序列	Gly13-Ser164
蛋白构建	Gly13-Ser164
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
分子量	17 KDa (reducing condition)

内毒素	< 1 EU/μg by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Histidine-HCl, 10% Trehalose, 0.05% Tween 80, pH5.5.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.

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IL-36 gamma Protein, Mouse, Recombinant

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