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Anti-PAX6 Antibody (9M633)

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Anti-PAX6 Antibody (9M633)
产品编号 TMAC-03078
别名 PAX 6, Paired box protein Pax-6, Oculorhombin, Aniridia type II protein, AN2

Anti-PAX6 Antibody (9M633) 是一种 Rabbit 抗体,靶向 PAX6。Anti-PAX6 Antibody (9M633) 可用于 WB,ICC/IF,IHC。

Anti-PAX6 Antibody (9M633)

Anti-PAX6 Antibody (9M633)

Rating icon 还可以
Anti-PAX6 Antibody (9M633)
产品编号 TMAC-03078 别名 PAX 6, Paired box protein Pax-6, Oculorhombin, Aniridia type II protein, AN2

Anti-PAX6 Antibody (9M633) 是一种 Rabbit 抗体,靶向 PAX6。Anti-PAX6 Antibody (9M633) 可用于 WB,ICC/IF,IHC。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-PAX6 Antibody (9M633) is a Rabbit antibody targeting PAX6. Anti-PAX6 Antibody (9M633) can be used in WB,ICC/IF,IHC.
别名PAX 6, Paired box protein Pax-6, Oculorhombin, Aniridia type II protein, AN2
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of PAX6 on Hela cells lysates using anti-PAX6 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded rat eyeball tissue using anti-PAX6 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-PAX6 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse eyeball tissue using anti-PAX6 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using anti-PAX6 antibody. Counter stained with hematoxylin.
应用
推荐剂量
WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Pax genes contain paired domains with strong homology to genes in Drosophila which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 48 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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