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Anti-Arp3/ACTR3 Antibody (2D811)
还可以产品编号 TMAH-00021
别名 ARP3 actin-related protein 3 homolog (yeast), ARP3
Anti-Arp3/ACTR3 Antibody (2D811) 是一种抗体，靶向 Arp3/ACTR3。Anti-Arp3/ACTR3 Antibody (2D811) 可用于 ELISA, WB。
Anti-Arp3/ACTR3 Antibody (2D811)
Anti-Arp3/ACTR3 Antibody (2D811)
还可以产品编号 TMAH-00021 别名 ARP3 actin-related protein 3 homolog (yeast), ARP3
Anti-Arp3/ACTR3 Antibody (2D811) 是一种抗体，靶向 Arp3/ACTR3。Anti-Arp3/ACTR3 Antibody (2D811) 可用于 ELISA, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,300 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-Arp3/ACTR3 Antibody (2D811) is an antibody targeting Arp3/ACTR3. Anti-Arp3/ACTR3 Antibody (2D811) can be used in ELISA, WB. |
| 别名 | ARP3 actin-related protein 3 homolog (yeast), ARP3 |
| Ig Type | Rabbit IgG |
| 克隆号 | 2D811 |
| 交叉反应 | Human, Mouse, Rat |
| 验证活性 | Western Blot -Positive WB detected in: PC-3 whole cell lysate, K562 whole cell lysate, HL-60 whole cell lysate, A549 whole cell lysate, Mouse Spleen whole cell lysate, Rat Spleen whole cell lysate -All lanes: Arp3 Antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 48 kDa -Observed band size: 48 kDa |
| 应用 | ELISA, WB |
| 推荐剂量 | WB:1:500-1:5000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Cell projection. Nucleus. Note=In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes) (PubMed:19109554). |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs). Plays a role in ciliogenesis. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Arp3 |
| 抗原种属 | Human |
| 基因ID | 10096 |
| Uniprot ID | |
| 研究领域 | Tags & Cell Markers, Immunology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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