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顶部生物活性储存和溶解信息计算器

Anti-GKAP Antibody (3C392)

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Anti-GKAP Antibody (3C392)
产品编号 TMAC-01665
别名 Protein kinase anchoring protein GKAP42, GKAP42, GKAP1_HUMAN, gkap1, G kinase-anchoring protein 1, G kinase anchoring protein 1, FKSG21, cGMP-dependent protein kinase-anchoring protein of 42 kDa, cGMP dependent protein kinase anchoring protein of 42 kDa, cGMP dependent protein kinase anchoring protein 42kDa

Anti-GKAP Antibody (3C392) 是一种 Mouse 抗体，靶向 GKAP。Anti-GKAP Antibody (3C392) 可用于 WB,ICC,IHC。

Anti-GKAP Antibody (3C392)

Anti-GKAP Antibody (3C392)

Rating icon 还可以
Anti-GKAP Antibody (3C392)
产品编号 TMAC-01665 别名 Protein kinase anchoring protein GKAP42, GKAP42, GKAP1_HUMAN, gkap1, G kinase-anchoring protein 1, G kinase anchoring protein 1, FKSG21, cGMP-dependent protein kinase-anchoring protein of 42 kDa, cGMP dependent protein kinase anchoring protein of 42 kDa, cGMP dependent protein kinase anchoring protein 42kDa

Anti-GKAP Antibody (3C392) 是一种 Mouse 抗体，靶向 GKAP。Anti-GKAP Antibody (3C392) 可用于 WB,ICC,IHC。

规格价格库存数量
50 μL
¥ 1,995
5日内发货
100 μL
¥ 2,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-GKAP Antibody (3C392) is a Mouse antibody targeting GKAP. Anti-GKAP Antibody (3C392) can be used in WB,ICC,IHC.
别名Protein kinase anchoring protein GKAP42, GKAP42, GKAP1_HUMAN, gkap1, G kinase-anchoring protein 1, G kinase anchoring protein 1, FKSG21, cGMP-dependent protein kinase-anchoring protein of 42 kDa, cGMP dependent protein kinase anchoring protein of 42 kDa, cGMP dependent protein kinase anchoring protein 42kDa
克隆号
3C392
交叉反应
Human
验证活性
1. Western blot analysis of DLGAP1 on HEK293 (1) and DLGAP1-hIgGFc transfected HEK293 (2) cell lysate using anti- DLGAP1 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti- DLGAP1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human esophagus tissue using anti- DLGAP1 antibody. Counter stained with hematoxylin.
4. ICC staining DLGAP1 (green) and actin filaments (red) in NIH/3T3 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC
IHC
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
研究背景The neurotransmitter glutamate facilitates neuronal signalling at excitatory synapses. Glutamate is released from the presynaptic membrane into the synaptic cleft. Across the synaptic cleft glutamate binds to both ion channels and metabotropic glutamate receptors at the postsynapse, which expedite downstream signalling in the neuron. The postsynaptic density, a highly specialized matrix, which is attached to the postsynaptic membrane, controls this downstream signalling. The postsynaptic density also resets the synapse after each synaptic firing. It is composed of numerous proteins including a family of Discs large associated protein 1, 2, 3 and 4 (DLGAP1-4) that act as scaffold proteins in the postsynaptic density. They link the glutamate receptors in the postsynaptic membrane to other glutamate receptors, to signalling proteins and to components of the cytoskeleton. With the central localisation in the postsynapse, the DLGAP family seems to play a vital role in synaptic scaling by regulating the turnover of both ionotropic and metabotropic glutamate receptors in response to synaptic activity. DLGAP family has been directly linked to a variety of psychological and neurological disorders. In this review we focus on the direct and indirect role of DLGAP family on schizophrenia as well as other brain diseases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
O14490
化学信息
分子量Theoretical: 109 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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