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Anti-Mono-methyl-Histone H2B (Lys5) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Mono-methyl-Histone H2B (Lys5)。Anti-Mono-methyl-Histone H2B (Lys5) Polyclonal Antibody 2 可用于 WB。
Anti-Mono-methyl-Histone H2B (Lys5) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Mono-methyl-Histone H2B (Lys5)。Anti-Mono-methyl-Histone H2B (Lys5) Polyclonal Antibody 2 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,565 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-Mono-methyl-Histone H2B (Lys5) Polyclonal Antibody 2 is a Rabbit antibody targeting Mono-methyl-Histone H2B (Lys5). Anti-Mono-methyl-Histone H2B (Lys5) Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Antigen affinity purification |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Histone post-translational modifications (PTMs) are key mechanisms in epigenetic regulation of chromatin structure, often referred to as the “histone code.” PTMs on histones include acetylation, methylation, phosphorylation, and several novel acylation modifications discovered in recent years. These histone modifications directly influence chromatin structure and the binding of transcription factors or other epigenetic regulators, thereby altering genomic stability and gene transcription. Histone methylation typically occurs on lysine and arginine residues of core histones. It can either promote or inhibit gene transcription, depending on whether methylation occurs on lysine or arginine residues and the number of methyl groups present (lysines can be mono-, di-, or trimethylated, while arginines can undergo mono-, symmetric, or asymmetric dimethylation). Lysine methylation in histones commonly occurs at lysine residues 4, 9, 27, 36, and 79 of histone H3, and at lysine 20 of histone H4. Arginine methylation typically occurs at arginine residues 2, 8, 17, and 26 of histone H3, and at arginine 3 of histone H4. Histone methyltransferases (HMTs) and histone demethylases (HDMs) are the primary regulators of methylation modifications. |
| 分子量 | Theoretical: 14 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |