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Anti-ADAM17 Antibody (6O847)
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产品编号 TMAC-00086
别名 TNF-alpha-converting enzyme, TNF-alpha convertase, Snake venom-like protease, EC 3.4.24.86, Disintegrin and metalloproteinase domain-containing protein 17, CSVP TACE, CD antigen CD156b, ADAM 17
Anti-ADAM17 Antibody (6O847) 是一种 Rabbit 抗体，靶向 ADAM17。Anti-ADAM17 Antibody (6O847) 可用于 WB,ICC/IF,IP,FCM。
Anti-ADAM17 Antibody (6O847)
Anti-ADAM17 Antibody (6O847)
还可以产品编号 TMAC-00086 别名 TNF-alpha-converting enzyme, TNF-alpha convertase, Snake venom-like protease, EC 3.4.24.86, Disintegrin and metalloproteinase domain-containing protein 17, CSVP TACE, CD antigen CD156b, ADAM 17
Anti-ADAM17 Antibody (6O847) 是一种 Rabbit 抗体，靶向 ADAM17。Anti-ADAM17 Antibody (6O847) 可用于 WB,ICC/IF,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-ADAM17 Antibody (6O847) is a Rabbit antibody targeting ADAM17. Anti-ADAM17 Antibody (6O847) can be used in WB,ICC/IF,IP,FCM. |
| 别名 | TNF-alpha-converting enzyme, TNF-alpha convertase, Snake venom-like protease, EC 3.4.24.86, Disintegrin and metalloproteinase domain-containing protein 17, CSVP TACE, CD antigen CD156b, ADAM 17 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of ADAM17 on Jurkat cells lysates using anti-ADAM17 antibody at 1/1,000 dilution. 2. ICC staining ADAM17 in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining ADAM17 in SKOV-3 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining ADAM17 in SW480 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of Hela cells with ADAM17 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; ICC/IF: 1:50-200; IP: 1:50; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Tumor necrosis factor β (TNFβ), also known as lymphotoxin, is a pleiotropic cytokine. TNFα, also known as cachetin, is a cytokine that binds to the same receptors, producing an array of effects similar to those of TNFβ. TNFβ and TNFα share 30% amino acid homology and have similar biological activities. TNFβ is produced by activated lymphocytes, including CD4+ T helper cell type 1 lymphocytes, CD8+ lymphocytes and certain B lymphoblastoid cell lines. TNFα is produced by several different cell types, including lymphocytes, neutrophils and macrophages. TNFβ and TNFα can modulate many immune and inflammatory functions while having the ability to inhibit tumor growth. TACE (for TNFα converting enzyme) is a metalloproteinase that cleaves the membrane-bound TNFα precursor to release soluble TNFα. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 93 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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