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Anti-Integrin alpha 5 beta 1 Polyclonal Antibody

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Anti-Integrin alpha 5 beta 1 Polyclonal Antibody
产品编号 TMAB-00976
别名 VLA5A, VLA-5, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α5 β 1, Integrin alpha 5 β1, FNRA, CD49e

Anti-Integrin alpha 5 beta 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Integrin alpha 5 beta 1。Anti-Integrin alpha 5 beta 1 Polyclonal Antibody 可用于 WB,FCM。

Anti-Integrin alpha 5 beta 1 Polyclonal Antibody

Anti-Integrin alpha 5 beta 1 Polyclonal Antibody

Rating icon 还可以
Anti-Integrin alpha 5 beta 1 Polyclonal Antibody
产品编号 TMAB-00976 别名 VLA5A, VLA-5, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α5 β 1, Integrin alpha 5 β1, FNRA, CD49e

Anti-Integrin alpha 5 beta 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Integrin alpha 5 beta 1。Anti-Integrin alpha 5 beta 1 Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Integrin alpha 5 beta 1 Polyclonal Antibody is a Rabbit antibody targeting Integrin alpha 5 beta 1. Anti-Integrin alpha 5 beta 1 Polyclonal Antibody can be used in WB,FCM.
别名VLA5A, VLA-5, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α5 β 1, Integrin alpha 5 β1, FNRA, CD49e
Ig Type
IgG
交叉反应
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Sheep)
验证活性
1. Blank control (blue line): MCF7 (fixed with 70% methanol overnight at 4°C).
Primary Antibody (green line): Rabbit Anti-Integrin Alpha V + Beta 1 antibody (TMAB-00976), Dilution: 1 μg/10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG.
Secondary Antibody (white blue line): Goat anti-rabbit IgG-PE, Dilution: 1 μg/test.
2. Sample:
Lane 1: A549 (Human) Cell Lysate at 30 μg
Lane 2: U251 (Human) Cell Lysate at 30 μg
Lane 3: Huvec (Human) Cell Lysate at 30 μg
Lane 4: SH-SY5Y (Human) Cell Lysate at 30 μg
Lane 5: U2os (Human) Cell Lysate at 30 μg
Lane 6: MCF-7 (Human) Cell Lysate at 30 μg
Lane 7: Jurkat (Human) Cell Lysate at 30 μg
Primary: Anti-Integrin Alpha V + Beta 1 (TMAB-00976) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 125 kDa
Observed band size: 125 kDa
应用
WB
FCM
推荐剂量
WB: 1:500-2000; FCM: 1μg /test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumour cells. ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.
抗原信息
免疫原
KLH conjugated synthetic Mixed peptides 915-948/1048(human Integrin αV)+ 21-70/798(human Integrin β1)
抗原种属
Human
基因ID
3685
Uniprot ID
P06756
研究领域
Integrins,Integrins,Platelets,Host Virus Interaction,T Lymphocytic Lineage
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

VLA5VLA 5integrin, α 5integrin, alpha 5integrin, a 5fibronectin receptor, α polypeptidefibronectin receptor, alpha polypeptidefibronectin receptor, a polypeptide

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