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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-uPAR/PLAUR Antibody (5W958)

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货号 TMAY-03148

别名 URKR, U-PAR, UPAR, plasminogen activator, urokinase receptor, CD87

Anti-uPAR/PLAUR Antibody (5W958) 是一种 Rabbit 抗体，靶向 uPAR/PLAUR。Anti-uPAR/PLAUR Antibody (5W958) 可用于 ELISA。

Anti-uPAR/PLAUR Antibody (5W958)

Anti-uPAR/PLAUR Antibody (5W958)

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Rating icon 还可以
货号 TMAY-03148 别名 URKR, U-PAR, UPAR, plasminogen activator, urokinase receptor, CD87

Anti-uPAR/PLAUR Antibody (5W958) 是一种 Rabbit 抗体，靶向 uPAR/PLAUR。Anti-uPAR/PLAUR Antibody (5W958) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-uPAR/PLAUR Antibody (5W958) is a Rabbit antibody targeting uPAR/PLAUR. Anti-uPAR/PLAUR Antibody (5W958) can be used in ELISA.
别名URKR, U-PAR, UPAR, plasminogen activator, urokinase receptor, CD87
Ig Type
Rabbit IgG
克隆号
5W958
反应种属
Mouse
特异性
Mouse uPAR/PLAUR
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse PLAUR / CD87 (rM PLAUR / CD87; TMPY-01257; NP_035243.1; Met1-Thr297).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and uPA levels in both resected tumor tissue and plasma are of independent prognostic significance for patient survival in several types of human cancer. This system has classically been thought to drive tumor progression by mediating directed extracellular proteolysis on the surface of migrating or invading cells, and intervening with this proteolysis by targeting uPAR has been proposed to represent a novel approach for inhibiting tumor progression. uPAR, also known as PLAUR or CD87, has been implicated in the growth, metastasis, and angiogenesis of several solid and hemotologic malignancies. uPAR is a highly glycosylated, 55-60kDa integral membrane protein linked to the plasma membrane by a glycosylphosphatidylinositol (GPI) anchor. It is part of a cell surface system that also consists of the serine protease uPA and several specific inhibitors (plasminogen activator inhibitors 1 and 2). Additionally, the analysis of CD87 (urokinase-type plasminogen activator receptor - uPAR) expression has a potential role in the diagnostic or prognostic work-up of several hematological malignancies, particularly acute leukemia and multiple myeloma.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse PLAUR / CD87 Protein (TMPY-01257)
抗原种属
Mouse
研究领域
Serine Proteases and Regulators
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

计算器

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关键词

CD-87CD 87
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