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Anti-BCAM Antibody (9E859)
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产品编号 TMAY-00512
别名 basal cell adhesion molecule (Lutheran blood group)
Anti-BCAM Antibody (9E859) 是一种 Rabbit 抗体，靶向 BCAM。Anti-BCAM Antibody (9E859) 可用于 ELISA,ELISA(Det)。
Anti-BCAM Antibody (9E859)
331 Anti-BCAM Antibody (9E859)
还可以产品编号 TMAY-00512 别名 basal cell adhesion molecule (Lutheran blood group)
Anti-BCAM Antibody (9E859) 是一种 Rabbit 抗体，靶向 BCAM。Anti-BCAM Antibody (9E859) 可用于 ELISA,ELISA(Det)。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 795 | 5日内发货 | |
| 100 μL | ¥ 2,289 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-BCAM Antibody (9E859) is a Rabbit antibody targeting BCAM. Anti-BCAM Antibody (9E859) can be used in ELISA,ELISA(Det). |
| 别名 | basal cell adhesion molecule (Lutheran blood group) |
| Ig Type | Rabbit IgG |
| 克隆号 | 9E859 |
| 交叉反应 | Human |
| 应用 | ELISA,ELISA(Det) |
| 推荐剂量 | ELISA: 1:5000-1:10000; ELISA(Det): 1:1000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human BCAM (rh BCAM; TMPY-02637; NP_005572.2; Met1-Ala547). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The Lutheran (Lu) blood group and basal cell adhesion molecule (BCAM) antigens are both carried by 2 glycoprotein isoforms of the immunoglobulin superfamily representing receptors for the laminin alpha(5) chain. It is a transmembrane receptor with five immunoglobulin-like domains in its extracellular region, and is therefore classified as a member of the immunoglobulin (Ig) gene family. In addition to red blood cells, Lu/BCAM proteins are expressed in endothelial cells of vascular capillaries and in epithelial cells of several tissues. BCAM/LU has a wide tissue distribution with a predominant expression in the basal layer of the epithelium and the endothelium of blood vessel walls. As designated as CD239 recently, BCAM and LU share a significant sequence similarity with the CD146 (MUC18) and CD166, and themselves are adhesion molecules that bind laminin with high affinity. Laminins are found in all basement membranes and are involved in cell differentiation, adhesion, migration, and proliferation. BCAM is upregulated following malignant transformation of some cell types in vivo and in vitro, thus being a candidate molecule involved in tumor progression. In addition, BCAM interacts with integrin in sickle red cells, and thus may potentially play a role in vaso-occlusive episodes. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | HRP |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Protein: Human BCAM protein (TMPY-02637) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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