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别名 抗DLL3抗体
Anti-DLL3 Antibody 是一种针对 Delta 样配体 3 (DLL3) 的人源化单克隆抗体。DLL3 在小细胞肺癌 (SCLC) 和高级别神经内分泌癌中特异性高表达,而在正常组织中几乎不表达。该抗体能够以高亲和力特异性结合 DLL3 胞外域并诱导快速内化。它是开发靶向疗法(如 ADC 或双特异性抗体)的重要工具,旨在通过内化作用将载荷输送至肿瘤细胞内,诱导细胞凋亡并抑制肿瘤生长。
Anti-DLL3 Antibody 是一种针对 Delta 样配体 3 (DLL3) 的人源化单克隆抗体。DLL3 在小细胞肺癌 (SCLC) 和高级别神经内分泌癌中特异性高表达,而在正常组织中几乎不表达。该抗体能够以高亲和力特异性结合 DLL3 胞外域并诱导快速内化。它是开发靶向疗法(如 ADC 或双特异性抗体)的重要工具,旨在通过内化作用将载荷输送至肿瘤细胞内,诱导细胞凋亡并抑制肿瘤生长。

| 产品描述 | Anti-DLL3 Antibody is a humanized monoclonal antibody targeting Delta-like ligand 3 (DLL3). DLL3 is specifically overexpressed in small cell lung cancer (SCLC) and high-grade neuroendocrine carcinomas, with minimal expression in normal tissues. This antibody binds to the extracellular domain of DLL3 with high affinity and induces rapid internalization. It serves as a critical tool for developing targeted therapies, such as ADCs or bispecific antibodies, aimed at delivering payloads into tumor cells to induce apoptosis and inhibit tumor growth. |
| 别名 | 抗DLL3抗体 |
| 反应种属 | Human |
| 应用 | ELISA FACS Functional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | IgG1 |
| 偶联 | Unconjugated |
| Uniprot ID | |
| 靶点 | DLL3 |
| 存储 |
对于不同动物的给药剂量换算,您也可以参考 更多