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Anti-MEN1 Antibody (5E903)

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产品编号 TMAH-00744
别名 SCG2, Menin, MEN 1

Anti-MEN1 Antibody (5E903) 是一种抗体,靶向 MEN1。Anti-MEN1 Antibody (5E903) 可用于 ELISA, WB。

Anti-MEN1 Antibody (5E903)

Anti-MEN1 Antibody (5E903)

Rating icon 还可以
产品编号 TMAH-00744 别名 SCG2, Menin, MEN 1

Anti-MEN1 Antibody (5E903) 是一种抗体,靶向 MEN1。Anti-MEN1 Antibody (5E903) 可用于 ELISA, WB。

规格价格库存数量
50 μL
¥ 1,315
5日内发货
100 μL
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-MEN1 Antibody (5E903) is an antibody targeting MEN1. Anti-MEN1 Antibody (5E903) can be used in ELISA, WB.
别名SCG2, Menin, MEN 1
Ig Type
Rabbit IgG
克隆号
5E903
交叉反应
Human
验证活性
Western Blot
-Positive WB detected in: PC-3 whole cell lysate, MCF-7 whole cell lysate, 293 whole cell lysate
-All lanes: MEN1 antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 69, 68, 64 kDa
-Observed band size: 75 kDa
应用
ELISA, WB
推荐剂量
WB:1:500-1:5000.
抗体种类
Monoclonal
亚细胞定位Nucleus. Note=Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression. May be involved in DNA repair.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human Menin
抗原种属
Human
基因ID
4221
Uniprot ID
研究领域
Epigenetics and Nuclear Signaling, Cancer
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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