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Anti-MEN1 Antibody (5E903) 是一种抗体,靶向 MEN1。Anti-MEN1 Antibody (5E903) 可用于 ELISA, WB。
Anti-MEN1 Antibody (5E903) 是一种抗体,靶向 MEN1。Anti-MEN1 Antibody (5E903) 可用于 ELISA, WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,315 | 5日内发货 | |
100 μL | ¥ 2,185 | 5日内发货 |
产品描述 | Anti-MEN1 Antibody (5E903) is an antibody targeting MEN1. Anti-MEN1 Antibody (5E903) can be used in ELISA, WB. |
别名 | SCG2, Menin, MEN 1 |
Ig Type | Rabbit IgG |
克隆号 | 5E903 |
交叉反应 | Human |
验证活性 | Western Blot -Positive WB detected in: PC-3 whole cell lysate, MCF-7 whole cell lysate, 293 whole cell lysate -All lanes: MEN1 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 69, 68, 64 kDa -Observed band size: 75 kDa |
应用 | ELISA, WB |
推荐剂量 | WB:1:500-1:5000. |
抗体种类 | Monoclonal |
亚细胞定位 | Nucleus. Note=Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression. May be involved in DNA repair. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide: Human Menin |
抗原种属 | Human |
基因ID | 4221 |
Uniprot ID | |
研究领域 | Epigenetics and Nuclear Signaling, Cancer |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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