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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Calpain 2 Polyclonal Antibody

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货号 TMAB-03576

Anti-Calpain 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Calpain 2。Anti-Calpain 2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Calpain 2 Polyclonal Antibody

Anti-Calpain 2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03576

Anti-Calpain 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Calpain 2。Anti-Calpain 2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Calpain 2 Polyclonal Antibody is a Rabbit antibody targeting Calpain 2. Anti-Calpain 2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Cow,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
组织特异性Ubiquitous.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Calpain, and m calpain, also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity (thus the mu) as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 and 2 are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. The calpains have papain like activity, thus the pain nomenclature. Both Calpain 1 and Calpain 2 are ubiquitously expressed, and are countered by the endogenous calpain inhibitor, calpastatin. Other calpain family members (calpain 94, ncl2, ncl3, etc) have more limited tissue distribution, and perhaps different functions. The calpain family members consist of a common small subunit (Calpain 4), and a large variable subunit. It is not clear that all calpains contain a small subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse Calpain 2
抗原种属
Mouse
基因名称
CAPN2
基因ID
824
蛋白名称
Calpain-2 catalytic subunit
功能
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
化学信息
分子量Theoretical: 78 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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