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Anti-OTUD5/DUBA Polyclonal Antibody

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货号 TMAB-09833

Anti-OTUD5/DUBA Polyclonal Antibody 是一种 Rabbit 抗体,靶向 OTUD5/DUBA。Anti-OTUD5/DUBA Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-OTUD5/DUBA Polyclonal Antibody

Anti-OTUD5/DUBA Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09833

Anti-OTUD5/DUBA Polyclonal Antibody 是一种 Rabbit 抗体,靶向 OTUD5/DUBA。Anti-OTUD5/DUBA Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-OTUD5/DUBA Polyclonal Antibody is a Rabbit antibody targeting OTUD5/DUBA. Anti-OTUD5/DUBA Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Expressed in various tissues, including the liver and placenta, as well as in peripheral blood leukocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human OTUD5/DUBA
抗原种属
Human
基因名称
OTUD5
基因ID
蛋白名称
OTU domain-containing protein 5
Uniprot ID
功能
Negative regulator of innate immune system. Has deubiquitinating activity that is directed towards 'Lys-63'-linked polyubiquitin chains. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production.
化学信息
分子量Theoretical: 61 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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