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TPSB2 Protein, Human, Recombinant (His)

Synonyms: Tryptase-2, Tryptase β-2, Tryptase II, Tryptase Beta-2, TPSB2, TPS2
货号 TMPJ-00542 一键复制产品信息
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Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.

TPSB2 Protein, Human, Recombinant (His)

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPJ-00542

别名 Tryptase-2, Tryptase β-2, Tryptase II, Tryptase Beta-2, TPSB2, TPS2

Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.

TPSB2 Protein, Human, Recombinant (His)
规格价格库存数量
5 μg
¥ 693
6-8日内发货
10 μg
¥ 1,170
6-8日内发货
20 μg
¥ 1,860
5日内发货
50 μg
¥ 3,470
5日内发货
100 μg
¥ 4,930
5日内发货
200 μg
¥ 7,350
5日内发货
500 μg
¥ 12,100
5日内发货
1 mg
¥ 17,300
5日内发货
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纯度: > 99.9%
颜色: 无色透明
性状: Solution

产品介绍


生物活性
产品描述
Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
生物活性
Loaded Anti-Human Tryptase mAb-Fc on AHC Biosensor, can bind Human TPSB2-His with an affinity constant of <10-3 nM as determined in BLI assay (Regularly tested)
TPSB2 Protein, Human, Recombinant (His)
研究背景
Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
种属
Human
表达系统
HEK293 Cells
标签C-6xHis
蛋白编号AAH29356.1
氨基酸序列Ala19-Pro275
蛋白构建Ala19-Pro275
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
TPSB2 Protein, Human, Recombinant (His)
缓冲液Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
别名Tryptase-2, Tryptase β-2, Tryptase II, Tryptase Beta-2, TPSB2, TPS2
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量30-35 KDa (reducing condition)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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