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Anti-Phospho-RAF1 (S43) Antibody (1U306) 是一种 Rabbit 抗体,靶向 Phospho-RAF1 (S43)。Anti-Phospho-RAF1 (S43) Antibody (1U306) 可用于 WB。
Anti-Phospho-RAF1 (S43) Antibody (1U306) 是一种 Rabbit 抗体,靶向 Phospho-RAF1 (S43)。Anti-Phospho-RAF1 (S43) Antibody (1U306) 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-Phospho-RAF1 (Ser43) Antibody (1U306) 是一种 Rabbit 抗体,靶向 Phospho-RAF1 (Ser43)。Anti-Phospho-RAF1 (Ser43) Antibody (1U306) 可用于 WB。 |
别名 | RAF1 (p-Ser43), RAF1 (p-S43), p-RAF1 (Ser43), p-RAF1 (S43), Phospho-RAF1 (S43) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of Phospho-Raf1 (S43) on different lysates using anti-Phospho-Raf1 (S43) antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3, Lane 2: 293T. |
应用 | |
推荐剂量 | WB: 1:1000-2000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk)and Raf-1. Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity. It is broadly expressed in nearly all cell lines tested to date and is the cellular homolog of v-Raf, the product of the transforming gene of the 3611 strain of murine sarcoma virus. The unregulated kinase activity of the v-Raf protein has been associated with transformation and mitogenesis while the activity of Raf-1 is normally suppressed by a regulatory N-terminal domain. Raf-1 is activated in response to activation of a variety of tyrosine kinase receptors as well as in response to pp60v-Src expression. There is accumulating evidence that Ras p21 may play a role in activation of Raf-1 and may play the role of the messenger from membrane tyrosine kinases to Raf-1. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human Raf1 around the phosphorylation site of Ser43 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 73 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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