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Anti-CD300A Antibody-FITC (9F620)

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产品编号 TMAY-02353F

Anti-CD300A Antibody-FITC (9F620) 是一种 FITC-conjugated Mouse 抗体,靶向 CD300A。Anti-CD300A Antibody-FITC (9F620) 可用于 FCM。

Anti-CD300A Antibody-FITC (9F620)

Anti-CD300A Antibody-FITC (9F620)

Rating icon 还可以
产品编号 TMAY-02353F

Anti-CD300A Antibody-FITC (9F620) 是一种 FITC-conjugated Mouse 抗体,靶向 CD300A。Anti-CD300A Antibody-FITC (9F620) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-CD300A Antibody-FITC (9F620) is a FITC-conjugated Mouse antibody targeting CD300A. Anti-CD300A Antibody-FITC (9F620) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
克隆号
9F620
交叉反应
Human
验证活性
Flow cytometric analysis of human CD300A expression on human whole blood monocytes. Human whole blood monocytes were stained with FITC-conjugated anti-Human CD300A. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD300A (rh CD300A; TMPY-02013; Q9UGN4-1; Met1-Gln178) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.09% sodium azide
研究背景CMRF35-like molecule 8, also known as CD300 antigen-like family member A, CMRF35-H9, Immunoglobulin superfamily member 12, Inhibitory receptor protein 60, NK inhibitory receptor, CD300a and CMRF35H, is a single-pass type I membrane protein which belongs to the CD300 family. The CD300 family of myeloid immunoglobulin receptors includes activating ( CD300b, CD300e ) and inhibitory members ( CD300a, CD300f ), as well as molecules presenting a negative charge within their transmembrane domain ( CD300c, CD300d ). CD300A / IGSF12 is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. It contains oneIg-like V-type ( immunoglobulin-like ) domain. CD300A / IGSF12 is an inhibitory receptor that may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells. CD300c signaling is partially mediated by a direct association with the immune receptor tyrosine-based activation motif-bearing adaptor FcεRγ. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from plasmacytoid dendritic cells (pDCs).
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/APC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Human CD300A protein (TMPY-02013)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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