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Anti-Surfactant protein D/SFTPD Antibody (2N50) 是一种 Rabbit 抗体,靶向 Surfactant protein D/SFTPD。Anti-Surfactant protein D/SFTPD Antibody (2N50) 可用于 ELISA,ELISA(Cap)。
Anti-Surfactant protein D/SFTPD Antibody (2N50) 是一种 Rabbit 抗体,靶向 Surfactant protein D/SFTPD。Anti-Surfactant protein D/SFTPD Antibody (2N50) 可用于 ELISA,ELISA(Cap)。
产品描述 | Anti-Surfactant protein D/SFTPD Antibody (2N50) is a Rabbit antibody targeting Surfactant protein D/SFTPD. Anti-Surfactant protein D/SFTPD Antibody (2N50) can be used in ELISA,ELISA(Cap). |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 2N50 |
交叉反应 | Mouse |
应用 | ELISA,ELISA(Cap) |
推荐剂量 | ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SFTPD (rM SFTPD; TMPY-01110; NP_033186.1; Met 1-Phe 374). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Surfactant pulmonary-associated protein D, also known as SFTPD and SP-D, is a member of the collectin family of C-type lectins that is synthesized in many tissues including respiratory epithelial cells in the lung, and contains one C-type lectin domain and one collagen-like domain. The polymorphic variation in the N-terminal domain of the SP-D molecule influences oligomerization, function, and the concentration of the molecule in serum. SFTPD is produced primarily by alveolar type II cells and nonciliated bronchiolar cells in the lung and is constitutively secreted into the alveoli where it influences surfactant homeostasis, effector cell functions, and host defense. It is upregulated in a variety of inflammatory and infectious conditions including Pneumocystis pneumonia and asthma. SFTPD is humoral molecules of the innate immune system, and is considered a functional candidate in chronic periodontitis. Besides, it is involved in the development of acute and chronic inflammation of the lung. Several human lung diseases are characterized by decreased levels of bronchoalveolar SFTPD. Thus, recombinant SFTPD has been proposed as a therapeutical option for cystic fibrosis, neonatal lung disease and smoking-induced emphysema. Furthermore, SFTPD serum levels can be used as disease activity markers for interstitial lung diseases. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse SFTPD protein( Catalog#50205-M08H) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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