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Anti-Surfactant protein D/SFTPD Antibody (2N50)

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产品编号 TMAY-03173

Anti-Surfactant protein D/SFTPD Antibody (2N50) 是一种 Rabbit 抗体,靶向 Surfactant protein D/SFTPD。Anti-Surfactant protein D/SFTPD Antibody (2N50) 可用于 ELISA,ELISA(Cap)。

Anti-Surfactant protein D/SFTPD Antibody (2N50)

Anti-Surfactant protein D/SFTPD Antibody (2N50)

Rating icon 还可以
产品编号 TMAY-03173

Anti-Surfactant protein D/SFTPD Antibody (2N50) 是一种 Rabbit 抗体,靶向 Surfactant protein D/SFTPD。Anti-Surfactant protein D/SFTPD Antibody (2N50) 可用于 ELISA,ELISA(Cap)。

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产品介绍

生物活性
产品描述
Anti-Surfactant protein D/SFTPD Antibody (2N50) is a Rabbit antibody targeting Surfactant protein D/SFTPD. Anti-Surfactant protein D/SFTPD Antibody (2N50) can be used in ELISA,ELISA(Cap).
Ig Type
Monoclonal Rabbit IgG
克隆号
2N50
交叉反应
Mouse
应用
ELISA,ELISA(Cap)
推荐剂量
ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SFTPD (rM SFTPD; TMPY-01110; NP_033186.1; Met 1-Phe 374).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Surfactant pulmonary-associated protein D, also known as SFTPD and SP-D, is a member of the collectin family of C-type lectins that is synthesized in many tissues including respiratory epithelial cells in the lung, and contains one C-type lectin domain and one collagen-like domain. The polymorphic variation in the N-terminal domain of the SP-D molecule influences oligomerization, function, and the concentration of the molecule in serum. SFTPD is produced primarily by alveolar type II cells and nonciliated bronchiolar cells in the lung and is constitutively secreted into the alveoli where it influences surfactant homeostasis, effector cell functions, and host defense. It is upregulated in a variety of inflammatory and infectious conditions including Pneumocystis pneumonia and asthma. SFTPD is humoral molecules of the innate immune system, and is considered a functional candidate in chronic periodontitis. Besides, it is involved in the development of acute and chronic inflammation of the lung. Several human lung diseases are characterized by decreased levels of bronchoalveolar SFTPD. Thus, recombinant SFTPD has been proposed as a therapeutical option for cystic fibrosis, neonatal lung disease and smoking-induced emphysema. Furthermore, SFTPD serum levels can be used as disease activity markers for interstitial lung diseases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse SFTPD protein( Catalog#50205-M08H)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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