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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MEGF10 Polyclonal Antibody

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货号 TMAB-08719

Anti-MEGF10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MEGF10。Anti-MEGF10 Polyclonal Antibody 可用于 WB。

Anti-MEGF10 Polyclonal Antibody

Anti-MEGF10 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08719

Anti-MEGF10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MEGF10。Anti-MEGF10 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-MEGF10 Polyclonal Antibody is a Rabbit antibody targeting MEGF10. Anti-MEGF10 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MEGF10
抗原种属
Human
基因名称
MEGF10
基因ID
84466
蛋白名称
Multiple epidermal growth factor-like domains protein 10
Uniprot ID
Q96KG7
功能
Involved in phagocytosis by macrophages of apoptotic cells. Cooperates with ABCA1 during engulfment. Destabilizes the oligomeric assemblies of the ABCA1 transporter. Plays a role in cell adhesion. Inhibits cell motility and cell proliferation in vitro. Promotes formation of large intracellular vacuoles.
化学信息
分子量Theoretical: 119 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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