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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Beclin 1 Antibody (6D646)

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货号 TMAB-03082

Anti-Beclin 1 Antibody (6D646) 是一种 Rabbit 抗体，靶向 Beclin 1。Anti-Beclin 1 Antibody (6D646) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Beclin 1 Antibody (6D646)

Anti-Beclin 1 Antibody (6D646)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03082

Anti-Beclin 1 Antibody (6D646) 是一种 Rabbit 抗体，靶向 Beclin 1。Anti-Beclin 1 Antibody (6D646) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Beclin 1 Antibody (6D646) is a Rabbit antibody targeting Beclin 1. Anti-Beclin 1 Antibody (6D646) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
6D646
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells.
组织特异性Ubiquitous.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Beclin 1 is the first identified mammalian gene to mediate autophagy and also has tumor suppressor and antiviral function. Autophagy, a process of bulk protein degradation through an autophagosomic lysosomal pathway, is important for differentiation, survival during nutrient deprivation, and normal growth control, and is often defective in tumor cells. Beclin 1 was originally isolated in a yeast two hybrid screen to identify Bcl 2 binding partners and maps to a tumor susceptibility locus on human chromosome 17q21 that is frequently monoallelically deleted in human breast, ovarian and prostate cancer. Beclin 1 encodes an evolutionarily conserved 52kDa coiled coil protein that is expressed in human muscle, epithelial cells and neurons.
抗原信息
免疫原
A synthesized peptide: human Beclin 1
抗原种属
Human
基因名称
BECN1
基因ID
8678
蛋白名称
Beclin-1
Uniprot ID
Q14457
功能
Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
化学信息
分子量Theoretical: 50 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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