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Anti-HGFA Antibody (9A829)

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产品编号 TMAY-00618
别名 肝细胞生长因子, RP11-529E1.2, MGC138397, MGC138395, HGFA

Anti-HGFA Antibody (9A829) 是一种 Rabbit 抗体,靶向 HGFA。Anti-HGFA Antibody (9A829) 可用于 ELISA。

Anti-HGFA Antibody (9A829)

Anti-HGFA Antibody (9A829)

Rating icon 还可以
产品编号 TMAY-00618 别名 肝细胞生长因子, RP11-529E1.2, MGC138397, MGC138395, HGFA

Anti-HGFA Antibody (9A829) 是一种 Rabbit 抗体,靶向 HGFA。Anti-HGFA Antibody (9A829) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-HGFA Antibody (9A829) is a Rabbit antibody targeting HGFA. Anti-HGFA Antibody (9A829) can be used in ELISA.
别名肝细胞生长因子, RP11-529E1.2, MGC138397, MGC138395, HGFA
Ig Type
Monoclonal Rabbit IgG
克隆号
9A829
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human HGFA / HGF Activator (rh HGFA / HGF Activator; TMPY-00821; NP_001519.1; Met 1-Ser 655).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the active heterodimeric form, which is a potent mitogen, motogen, and morphogen for liver cells, epithelial cells, and endothelial cells. HGFA is synthesized and secreted by the liver and circulates in the plasma as an inactive single-chain zymogen in normal states. The zymogen is cleaved by thrombin or thermolysin through the endoproteolytic process and forms an active heterodimer linked by a disulfide bond. In turn, the active protease can be inhibited by HGFA inhibitors (HAIs) including HAI-1 and HAI-2. Besides, the HGFA zymogen acquires a strong affinity upon activation and thus may ensure the local action in tissue regeneration in the liver, kidney, and skin. It has been reported that activation of HGF is a critical limiting step in the HGF/SF-induced signaling pathway mediated by Met, and accordingly, aberrant expression of HGFA is implicated in tumorigenesis and progression.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human HGFA protein (TMPY-00821)
抗原种属
Human
研究领域
Serine Proteases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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