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Anti-HGFA Antibody (9A829) 是一种 Rabbit 抗体,靶向 HGFA。Anti-HGFA Antibody (9A829) 可用于 ELISA。
Anti-HGFA Antibody (9A829) 是一种 Rabbit 抗体,靶向 HGFA。Anti-HGFA Antibody (9A829) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μL | ¥ 2,279 | 5日内发货 |
产品描述 | Anti-HGFA Antibody (9A829) is a Rabbit antibody targeting HGFA. Anti-HGFA Antibody (9A829) can be used in ELISA. |
别名 | 肝细胞生长因子, RP11-529E1.2, MGC138397, MGC138395, HGFA |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9A829 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human HGFA / HGF Activator (rh HGFA / HGF Activator; TMPY-00821; NP_001519.1; Met 1-Ser 655). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | HGF activator (HGFA) is a serum-derived serine protease and belongs to the peptidase family S1.HGFA is responsible for the conversion of hepatocyte growth factor (HGF), from the inactive single-chain precursor to the active heterodimeric form, which is a potent mitogen, motogen, and morphogen for liver cells, epithelial cells, and endothelial cells. HGFA is synthesized and secreted by the liver and circulates in the plasma as an inactive single-chain zymogen in normal states. The zymogen is cleaved by thrombin or thermolysin through the endoproteolytic process and forms an active heterodimer linked by a disulfide bond. In turn, the active protease can be inhibited by HGFA inhibitors (HAIs) including HAI-1 and HAI-2. Besides, the HGFA zymogen acquires a strong affinity upon activation and thus may ensure the local action in tissue regeneration in the liver, kidney, and skin. It has been reported that activation of HGF is a critical limiting step in the HGF/SF-induced signaling pathway mediated by Met, and accordingly, aberrant expression of HGFA is implicated in tumorigenesis and progression. |
偶联 | Unconjugated |
免疫原 | Recombinant Human HGFA protein (TMPY-00821) |
抗原种属 | Human |
研究领域 | Serine Proteases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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