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Anti-Desmocollin 2/DSC2 Antibody (2L770)
还可以产品编号 TMAY-01189
Anti-Desmocollin 2/DSC2 Antibody (2L770) 是一种 Mouse 抗体，靶向 Desmocollin 2/DSC2。Anti-Desmocollin 2/DSC2 Antibody (2L770) 可用于 ELISA。
Anti-Desmocollin 2/DSC2 Antibody (2L770)
Anti-Desmocollin 2/DSC2 Antibody (2L770)
还可以产品编号 TMAY-01189
Anti-Desmocollin 2/DSC2 Antibody (2L770) 是一种 Mouse 抗体，靶向 Desmocollin 2/DSC2。Anti-Desmocollin 2/DSC2 Antibody (2L770) 可用于 ELISA。
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抗原信息
| 产品描述 | Anti-Desmocollin 2/DSC2 Antibody (2L770) is a Mouse antibody targeting Desmocollin 2/DSC2. Anti-Desmocollin 2/DSC2 Antibody (2L770) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 2L770 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DSC2 (rh DSC2; Q02487-1Met1-Arg684). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | DSC2 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. Like other desmocollins, murine DSC2 has two products, Dsc2a and Dsc2b, produced by alternative splicing of a 46 bp exon which encodes 11 COOH-terminal aa followed by an in-frame stop codon. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in DSC2 are associated with arrhythmogenic right ventricular dysplasia-11. DSC2 is Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. DSC2 may contribute to epidermal cell positioning by mediating differential adhesiveness between cells that express different isoforms. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human DSC2 Protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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