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Anti-SLAMF6 Antibody (3Z84)

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Anti-SLAMF6 Antibody (3Z84)
产品编号 TMAY-02160
别名 SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352

Anti-SLAMF6 Antibody (3Z84) 是一种 Rabbit 抗体,靶向 SLAMF6。Anti-SLAMF6 Antibody (3Z84) 可用于 IHC-P。

Anti-SLAMF6 Antibody (3Z84)
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Anti-SLAMF6 Antibody (3Z84)

Rating icon 还可以
Anti-SLAMF6 Antibody (3Z84)
产品编号 TMAY-02160 别名 SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352

Anti-SLAMF6 Antibody (3Z84) 是一种 Rabbit 抗体,靶向 SLAMF6。Anti-SLAMF6 Antibody (3Z84) 可用于 IHC-P。

规格价格库存数量
20 μL
¥ 790
5日内发货
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-SLAMF6 Antibody (3Z84) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (3Z84) can be used in IHC-P.
别名SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Ig Type
Rabbit IgG
克隆号
3Z84
交叉反应
Human
验证活性
1. Immunochemical staining of human SLAMF6 in human tonsil with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of human SLAMF6 in human spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
3. Immunochemical staining of human SLAMF6 in human appendix with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
应用
IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108 / SLAMF6 (rh Ly108 / SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human Ly108 / SLAMF6 protein (TMPY-01914)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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