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顶部产品介绍化学信息储存和溶解信息计算器技术支持

SIRP gamma Protein, Human, Recombinant (His & Avi), Biotinylated

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货号 TMPK-00251

别名 SIRPG, SIRP-B2, SIRP γ/CD172g, SIRP γ, SIRP β2, SIRP β 2, SIRP gamma, SIRP beta 2, FLJ42230, Cripto-1, CD172g, bA77C3.1

Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRP gamma Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.7 kDa and the accession number is Q9P1W8.

SIRP gamma Protein, Human, Recombinant (His & Avi), Biotinylated
其他形式的 “SIRP gamma Protein, Human, Recombinant (His & Avi), Biotinylated”:
SIRP gamma Protein, Human, Recombinant (hFc)
SIRP beta 2 Protein, Human, Recombinant (hFc)
SIRP gamma Protein, Human, Recombinant (His & Avi)
SIRP gamma Protein, Human, Recombinant (His)
SIRP gamma Protein, Cynomolgus, Recombinant (His)
SIRP gamma Protein, Cynomolgus, Recombinant (hFc)

SIRP gamma Protein, Human, Recombinant (His & Avi), Biotinylated

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货号 TMPK-00251 别名 SIRPG, SIRP-B2, SIRP γ/CD172g, SIRP γ, SIRP β2, SIRP β 2, SIRP gamma, SIRP beta 2, FLJ42230, Cripto-1, CD172g, bA77C3.1

Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRP gamma Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.7 kDa and the accession number is Q9P1W8.

规格价格库存数量
5 μg
¥ 568
6-8日内发货
10 μg
¥ 928
6-8日内发货
20 μg
¥ 1,530
5日内发货
50 μg
¥ 2,970
5日内发货
100 μg
¥ 5,180
5日内发货
200 μg
¥ 9,390
5日内发货
500 μg
¥ 20,700
5日内发货
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产品介绍

生物活性
产品描述
Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRP gamma Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.7 kDa and the accession number is Q9P1W8.
生物活性
Immobilized Biotinylated Human SIRP Gamma, His Tag at 1μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Human CD47, hFc Tag with the EC50 of 0.27μg/ml determined by ELISA.
研究背景
Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号Q9P1W8
蛋白构建Glu29-Pro360
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名SIRPG, SIRP-B2, SIRP γ/CD172g, SIRP γ, SIRP β2, SIRP β 2, SIRP gamma, SIRP beta 2, FLJ42230, Cripto-1, CD172g, bA77C3.1
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量39.7 kDa (predicted). Due to glycosylation, the protein migrates to 48-53 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

SIRP b 2FLJ-42230FLJ 42230
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