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Anti-Transferrin Receptor/TFRC Antibody (1W119)
还可以产品编号 TMAY-03442
Anti-Transferrin Receptor/TFRC Antibody (1W119) 是一种 Rabbit 抗体，靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody (1W119) 可用于 IHC-P。
Anti-Transferrin Receptor/TFRC Antibody (1W119)
Anti-Transferrin Receptor/TFRC Antibody (1W119)
还可以产品编号 TMAY-03442
Anti-Transferrin Receptor/TFRC Antibody (1W119) 是一种 Rabbit 抗体，靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody (1W119) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Transferrin Receptor/TFRC Antibody (1W119) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (1W119) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1W119 |
| 交叉反应 | Mouse |
| 验证活性 | 1. Immunochemical staining of mouse TFRC in mouse liver with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of mouse TFRC in mouse kidney with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 3. Immunochemical staining of mouse TFRC in mouse small intestine with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Transferrin Receptor / TFRC (rM Transferrin Receptor / TFRC; TMPY-02294; Q62351; Cys89-Phe763). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse Transferrin Receptor / TFRC Protein (TMPY-02294) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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