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H-Tyr-Ala-OH

Name: H-Tyr-Ala-OH
Brand: TargetMol
SKU: T40840
Price: 112 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: Tyrosylalanine, H-Tyr-Ala-OH

货号 T40840Cas号 730-08-5 一键复制产品信息纯度: 99.74%

很棒

H-Tyr-Ala-OH (Tyrosylalanine) 是一种L-酪氨酸和L-丙氨酸组成的二肽。

H-Tyr-Ala-OH

一键复制产品信息

很棒

纯度: 99.74%

货号 T40840Cas号 730-08-5

别名 Tyrosylalanine, H-Tyr-Ala-OH

H-Tyr-Ala-OH (Tyrosylalanine) 是一种L-酪氨酸和L-丙氨酸组成的二肽。

规格	价格	库存
2 mg	¥ 112	现货
5 mg	¥ 169	现货
10 mg	¥ 239	现货
25 mg	¥ 418	现货
50 mg	¥ 597	现货
100 mg	¥ 878	现货
200 mg	¥ 1,280	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

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纯度: 99.74%

颜色: 白色

性状: Solid

资源下载: COA HNMR HPLC产品操作手册

产品介绍

H-Tyr-Ala-OH AI Summary

H-Tyr-Ala-OH demonstrates a broad spectrum of bioactivities targeting various biological entities and processes. It has an IC50 greater than 500,000.0 nM for inhibiting Plasmodium falciparum Pfmrk. The compound shows a binding affinity at PKA with a Ki value of 2300.0 nM and inhibits CaM-KKbeta with a Ki of 13000.0 nM. Additionally, it binds to MLCK and PKC with Ki values of 150000.0 nM and 40000.0 nM, respectively, and inhibits PKG with a Ki of 1300.0 nM. It also interact with multiple kinases, altering the thermal stability of numerous proteins involved in cellular signaling. In microbial assays, H-Tyr-Ala-OH inhibits Escherichia coli D-alanine-D-alanine ligase B with an 85.3% inhibition rate at 2 mM concentration and inhibits Staphylococcus sp. APH(3')-3a with a Ki of 49000.0 nM. It is being evaluated for its effect on Polymerase Kappa with a potency of 21192.3 nM. Moreover, the compound shows a binding affinity to human CDK2 with a Kd of 286000.0 nM and exhibits antiviral activity against SARS-CoV-2 with IC50 values greater than 20000.0 nM. Lastly, H-Tyr-Ala-OH inhibits human HDAC6 activity as evidenced by inhibition percentages of -0.06% and -6.2% in enzymatic assays with commercial and custom peptide substrates, respectively..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Tyrosylalanine (H-Tyr-Ala-OH), a dipeptide comprising L-tyrosine and L-alanine, is referenced in studies [1] [2].
别名	Tyrosylalanine, H-Tyr-Ala-OH

化学信息

分子量	252.27
分子式	C₁₂H₁₆N₂O₄
CAS No.	730-08-5
Smiles	C([C@@H](C(N[C@H](C(O)=O)C)=O)N)C1=CC=C(O)C=C1
Sequence	Tyr-Ala
Sequence Short	YA

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

H2O: 120 mg/mL (475.68 mM), Sonication is recommended.

溶液配制表

H2O

	1mg	5mg	10mg	50mg
1 mM	3.9640 mL	19.8200 mL	39.6401 mL	198.2003 mL
5 mM	0.7928 mL	3.9640 mL	7.9280 mL	39.6401 mL
10 mM	0.3964 mL	1.9820 mL	3.9640 mL	19.8200 mL
20 mM	0.1982 mL	0.9910 mL	1.9820 mL	9.9100 mL
50 mM	0.0793 mL	0.3964 mL	0.7928 mL	3.9640 mL
100 mM	0.0396 mL	0.1982 mL	0.3964 mL	1.9820 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。