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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Claudin 12 Polyclonal Antibody

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货号 TMAB-04419

Anti-Claudin 12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Claudin 12。Anti-Claudin 12 Polyclonal Antibody 可用于 WB。

Anti-Claudin 12 Polyclonal Antibody

Anti-Claudin 12 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04419

Anti-Claudin 12 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Claudin 12。Anti-Claudin 12 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-Claudin 12 Polyclonal Antibody is a Rabbit antibody targeting Claudin 12. Anti-Claudin 12 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction > tight junction. Cell membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The claudin superfamily consists of many structurally related proteins that are important structural and functional components of tight junctions. Claudin-12, also known as CLDN12, is a 244 amino acid multi-pass membrane protein that is expressed in the brain, duodenum, jejunum, ileum, and colon. Claudin-12 localizes to cell junctions and may be involved in tight junction integrity by regulating hyperammonemia. Ammonia can alter brain capillary endothelial cell gene expression and transporter function. Claudin-12 is upregulated in enterocytes through vitamin D receptors which strongly suggest that claudin-12 forms paracellular Ca(2+) channels in intestinal epithelia and may be critical for vitamin D-dependent calcium homeostasis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Claudin 12
抗原种属
Human
基因名称
CLDN12
基因ID
9069
蛋白名称
Claudin-12
Uniprot ID
P56749
功能
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
化学信息
分子量Theoretical: 24 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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