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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-A2AR Polyclonal Antibody

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货号 TMAB-00016

别名 RDC8, ADORA2A, ADORA2, ADORA 2, Adenosine A2a R, A2aR

Anti-A2AR Polyclonal Antibody 是一种 Rabbit 抗体，靶向 A2AR。Anti-A2AR Polyclonal Antibody 可用于 WB。

Anti-A2AR Polyclonal Antibody

Anti-A2AR Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-00016 别名 RDC8, ADORA2A, ADORA2, ADORA 2, Adenosine A2a R, A2aR

Anti-A2AR Polyclonal Antibody 是一种 Rabbit 抗体，靶向 A2AR。Anti-A2AR Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-A2AR Polyclonal Antibody is a Rabbit antibody targeting A2AR. Anti-A2AR Polyclonal Antibody can be used in WB.
别名RDC8, ADORA2A, ADORA2, ADORA 2, Adenosine A2a R, A2aR
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit)
验证活性
25 μg total protein per Lane of various lysates probed with Adenosine Receptor A2a polyclonal antibody, unconjugated (TMAB-00016) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
抗原信息
免疫原
KLH conjugated synthetic peptide: human A2AR
抗原种属
Human
基因名称
ADORA2A
基因ID
135
蛋白名称
Adenosine receptor A2a
Uniprot ID
P29274
研究领域
Metabolism,Phagocytosis,Inflammatory mediators,Regulatory,Phagocytosis,Apoptosis,Neuroregeneration,More GPCR,GPCR
功能
Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

RDC-8RDC 8ADORA-2
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