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顶部生物活性储存和溶解信息计算器

Anti-SLAMF6 Antibody (2C420)

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产品编号 TMAY-02161
别名 SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352

Anti-SLAMF6 Antibody (2C420) 是一种 Rabbit 抗体，靶向 SLAMF6。Anti-SLAMF6 Antibody (2C420) 可用于 FCM。

Anti-SLAMF6 Antibody (2C420)

Anti-SLAMF6 Antibody (2C420)

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产品编号 TMAY-02161 别名 SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352

Anti-SLAMF6 Antibody (2C420) 是一种 Rabbit 抗体，靶向 SLAMF6。Anti-SLAMF6 Antibody (2C420) 可用于 FCM。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-SLAMF6 Antibody (2C420) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (2C420) can be used in FCM.
别名SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Ig Type
Rabbit IgG
克隆号
2C420
交叉反应
Human
特异性
Human SLAMF6
验证活性
Flow cytometric analysis of Human SLAMF6(CD352) expression on human whole blood lymphocytes. Cells were stained with purified anti-Human SLAMF6(CD352), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
应用FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108/SLAMF6 (rh Ly108/SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human Ly108/SLAMF6 Protein (TMPY-01914)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

SF-2000SF 2000CD-352CD 352

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