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Anti-Kininogen 1 Antibody (3N12) 是一种 Rabbit 抗体,靶向 Kininogen 1。Anti-Kininogen 1 Antibody (3N12) 可用于 ELISA。
Anti-Kininogen 1 Antibody (3N12) 是一种 Rabbit 抗体,靶向 Kininogen 1。Anti-Kininogen 1 Antibody (3N12) 可用于 ELISA。
产品描述 | Anti-Kininogen 1 Antibody (3N12) is a Rabbit antibody targeting Kininogen 1. Anti-Kininogen 1 Antibody (3N12) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 3N12 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse KNG1 / Kininogen 1 (rM KNG1 / Kininogen 1; TMPY-01606; NP_001095882.1; Glu 21-Ser 480). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Kininogen-1, also known as high molecular weight kininogen, Williams-Fitzgerald-Flaujeac factor, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, KNG1, and BDK, is a secreted protein that contains three cystatin domains. Kininogen-1 / KNG1 is a protein from the blood coagulation system as well as the kinin-kallikrein system. It is a protein that adsorbs to the surface of biomaterials that come in contact with blood. Kininogen-1 / KNG1 circulates throughout the blood and quickly adsorbs to the material surfaces. Kininogen-1 / KNG1 is one of the early participants of the intrinsic pathway of coagulation, together with Factor XII (Hageman factor) and prekallikrein. Kininogen-1 / KNG1 is one of the kininogens, a class of proteins. As with many other coagulation proteins, the protein was initially named after the patients in whom deficiency was first observed. When the clinical data were combined, it turned out that all patients had a deficiency of the same protein. Defects in KNG1 are the cause of high molecular weight kininogen deficiency (HMWK deficiency) which is an autosomal recessive coagulation defect. Patients with HWMK deficiency do not have a hemorrhagic tendency, but they exhibit abnormal surface-mediated activation of fibrinolysis. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse KNG1 / Kininogen 1 protein (TMPY-01606) |
抗原种属 | Mouse |
研究领域 | Neurotransmitter Associated Enzymes |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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