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Anti-MUC17 Antibody是一种在CHO细胞中表达的人源化单克隆抗体,靶向跨膜粘蛋白MUC17(也称为MUC3G)。Anti-MUC17 Antibody特异性识别MUC17的胞外结构域。MUC17在多种胃肠道肿瘤(尤其是胃癌和结直肠癌)中呈高表达。Anti-MUC17 Antibody通过与细胞表面的MUC17结合,介导抗体依赖性细胞介导的细胞毒性作用 (ADCC),并可作为载体将偶联的治疗载荷(如在ADC研究中)定向递送至肿瘤细胞内部。
别名 抗MUC17抗体
Anti-MUC17 Antibody是一种在CHO细胞中表达的人源化单克隆抗体,靶向跨膜粘蛋白MUC17(也称为MUC3G)。Anti-MUC17 Antibody特异性识别MUC17的胞外结构域。MUC17在多种胃肠道肿瘤(尤其是胃癌和结直肠癌)中呈高表达。Anti-MUC17 Antibody通过与细胞表面的MUC17结合,介导抗体依赖性细胞介导的细胞毒性作用 (ADCC),并可作为载体将偶联的治疗载荷(如在ADC研究中)定向递送至肿瘤细胞内部。

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | 待询 | 待询 | |
| 5 mg | 待询 | 待询 |
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| 产品描述 | Anti-MUC17 Antibody is a humanized monoclonal antibody expressed in CHO cells targeting the transmembrane mucin MUC17 (also known as MUC3G). This product specifically recognizes the extracellular domain of MUC17. MUC17 is overexpressed in various gastrointestinal tumors, particularly gastric and colorectal cancers. The antibody binds to MUC17 on the cell surface, mediating antibody-dependent cellular cytotoxicity (ADCC), and serves as a vehicle for the targeted delivery of conjugated therapeutic payloads (as in ADC research) into tumor cells. |
| 别名 | 抗MUC17抗体 |
| 反应种属 | Human |
| 应用 | ELISAFACSFunctional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | IgG1 |
| 偶联 | Unconjugated |
| Uniprot ID | |
| 靶点 | MUC17 |
| 存储 | Store at -20°C Shipping with blue ice. 实际储存温度请以COA为准 |
对于不同动物的给药剂量换算,您也可以参考 更多